Rilpivirine

Qanacsan

• Kahor qaadashada rilpivirine,
• Rilpivirine waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan jooji qaadashada rilpivirine isla markaana wac dhakhtarkaaga isla markiiba ama aad u hesho daaweyn caafimaad oo degdeg ah:

Rilpivirine waxaa loo isticmaalaa dawooyin kale si loogu daaweeyo fayraska difaaca jirka ee nooca 1 (HIV-1) ee dadka waaweyn qaarkood iyo carruurta 12 sano jirka ah ama ka weyn oo miisaankoodu ugu yaraan yahay 77 lb (35 kg) oo aan helin dawada antiretroviral waagii hore. Waxaa sidoo kale loo isticmaalaa cabotegravir (Vocabria) sida daaweynta muddada-gaaban ee cudurka-HIV-1 ee dadka waaweyn qaarkood. Rilpivirine waxay ku jirtaa nooc daawooyin ah oo loo yaqaan non-nucleoside reverse transcriptase inhibitors (NNRTIs). Waxay ku shaqeysaa iyadoo la yareeyo qadarka HIV ee dhiiga ku jira. In kastoo rilpivirine uusan bogsiinaynin HIV, waxay yareyn kartaa fursaddaada inaad kuhesho cillad difaac la'aanta jirka (AIDS) iyo cudurrada la xiriira HIV sida infekshannada halista ah ama kansarka. Qaadashada daawooyinkan oo ay weheliso ku-dhaqan galmo badbaado leh iyo isbeddello kale oo hab-nololeed ah ayaa yareyn kara halista ah u-qaadista (faafinta) fayraska HIV dadka kale.

Rilpivirine waxay u timaadaa sidii kiniin afka laga qaato. Waxaa badanaa lagu qaataa cunto (ma aha oo keliya cabitaanka borotiinka) hal mar maalintii. Marka rilpivirine lala qaato cabotegravir, badanaa waxaa la qaataa hal mar maalintii iyadoo la cunayo. Qaado rilpivirine keligaa ama raac cabotegravir qiyaastii isla waqtigaas maalin kasta. Rilpivirine waxaa lala socdaa cabotegravir ilaa hal bil (ugu yaraan 28 maalmood) ka hor intaan lagu bilaabin daaweynta qaababka duritaanka ee muddada dheer ee daawooyinkan ama ilaa 2 bilood haddii jadwalka daaweynta la isku duro la seego in ka badan 7 maalmood. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado rilpivirine sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Rilpivirine ayaa xakameysa HIV laakiin ma daaweyso. Sii wad inaad qaadato daawada rilpivirine xitaa haddii aad caafimaad qabtid. Ha u joojin qaadashada daawada rilpivirine adiga oo aan la hadlin dhakhtarkaaga. Marka sahaydaada rilpivirine ay bilaabato inay hoos u dhacdo, wax badan ka hel dhakhtarkaaga ama farmashiistahaaga. Haddii aad seegto qiyaasaha ama aad joojiso qaadashada daawada rilpivirine, xaaladdaadu way sii adkaan doontaa in la daweeyo.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada rilpivirine,

• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay rilpivirine, dawooyinka kale, ama wax ka mid ah maaddooyinka ku jira kiniiniyada rilpivirine. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid dexamethasone (Decadron); daawooyinka qalalaasaha oo ay ku jiraan carbamazepine (Carbatrol, Epitol, Euetro, Tegretol, Teril), oxcarbazepine (Trileptal), phenobarbital (Luminal), ama phenytoin (Dilantin, Phenytek); proton pump inhibitors oo ay ku jiraan dexlansoprazole (Dexilant), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), ama rabeprazole (Aciphex); rifampin (Rifater, Rifamate, Rimactane, Rifadin); rifapentine (Priftin); iyo johannesört wort. Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan daawada rilpivirine haddii aad qaadanaysid mid ama in kabadan oo daawooyinkan ah.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: daawooyinka antifungal, oo ay ku jiraan fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), iyo voriconazole (Vfend); amiodarone (Nexterone, Pacerone); anagrelide (Agrylin); chloroquine; chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram (Celexa); clarithromycin (Biaxin); sibibramramide (Norpace); dofetilide (Tikosyn); donepezil (Aricept); erythromycin (E-Mycin, Eryc, Ery-Tab, PCE, Pediazole); flecainide (Tambocor); haloperidol (Haldol); ibutilide (Corvert); levofloxacin; methadone (Dolophine); moxifloxacin (Velox); nelfinavir (Viracept); ondansetron (Zuplenz, Zofran); dawooyinka kale ee NNRTIs ee lagu daaweeyo HIV / AIDS; pentamidine (NebuPent, Pentam); pimozide (Orap); procainamide; quinidine (oo ku taal Nuedexta); rifabutin (Mycobutin); sotalol (Betapace, Sorine, Sotylize); telithromycin (Ketek); iyo thioridazine. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara rilpivirine, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• haddii aad qaadanaysid dawooyin ka kooban dawooyin ka kooban kalsiyam, magnesium, ama aluminium (Maalox, Mylanta, Tums, kuwa kale), qaado ugu yaraan 2 saacadood ka hor ama 4 saacadood ka dib rilpivirine.
• haddii aad daawo u qaadanaysid calool xanuun, laab xanuun, ama boogaha sida cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ama ranitidine (Zantac), qaado ugu yaraan 12 saacadood kahor ama uguyaraan 4 saacadood kadib rilpivirine .
• haddii aad qaadanayso didanosine (Videx), qaado ugu yaraan 2 saacadood ka hor ama ugu yaraan 4 saacadood ka dib rilpivirine.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa isku buuqday ama cudurro kale oo maskaxda ah, cudur beerka ah, oo ay ku jiraan cagaarshowga B ama C, ama cudur kelyaha ah.
• u sheeg dhakhtarkaaga haddii aad uur leedahay ama aad qorsheyneyso inaad uur yeelato. Haddii aad uur yeelato inta aad qaadanaysid daawada loo yaqaan 'rilpivirine', wac dhakhtarkaaga. U sheeg dhakhtarkaaga haddii aad naas nuujiso. Waa inaadan naas nuujin haddii aad qabtid cudurka HIV ama haddii aad qaadanaysid daawada loo yaqaan 'rilpivirine'.
• waa inaad ogaataa in dufanka jirkaagu uu kordhi karo ama u dhaqaaqi karo meelo kala duwan oo jirkaaga ah sida naasahaaga, dhabarka kore iyo qoorta, ama hareeraha jirkaaga. Lumitaan lugaha, gacmaha, iyo wajiga ayaa waliba dhici kara.
• waa inaad ogaataa in rilpivirine ay sababi karto isbedel fikirkaaga, dhaqankaaga, ama caafimaadka maskaxdaada. Isla markiiba wac dhakhtarkaaga haddii aad isku aragto mid ka mid ah astaamaha soo socda inta aad qaadanaysid daawada rilpivirine: niyad jab cusub ama ka sii daraysa; dareemid murugo, rajo la'aan, walaac, ama nasasho la'aan; ama aad ka fikirto inaad is disho ama aad qorsheysato ama aad isku daydo inaad sidaas sameyso. Hubso in qoyskaagu ogyahay astaamaha halista ah si ay ugu wici karaan dhakhtarkaaga haddii aadan awoodin inaad keligaa daaweyn raadsato.
• Waa inaad ogaataa inta aad qaadanaysid dawooyinka lagu daaweynayo infekshinka HIV, nidaamkaaga difaaca ayaa laga yaabaa inuu sii xoogeysto oo uu bilaabo inuu la dagaallamo infekshannada kale ee horay ugu jiray jirkaaga ama u sababi kara xaalado kale inay dhacaan. Tani waxay kugu sababi kartaa inaad yeelato calaamadaha cuduradaas ama xaaladahaas. Haddii aad leedahay calaamado cusub ama ka sii daraya ka dib markii aad bilawday daaweynta rilpivirine, hubi inaad u sheegto dhakhtarkaaga.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Qaado qiyaasta aad seegtay sida ugu dhakhsaha badan ee aad u xasuusato, adiga oo cunaya. Si kastaba ha noqotee, haddii ay in ka badan 12 saacadood ahayd markii ugu dambeysay ee aad qaadatay, ka bood qiyaasta la seegay oo sii wad jadwalkaaga qaadashada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Rilpivirine waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• dhibaato xagga hurdada ama hurdada ah
• madax xanuun
• lallabbo
• matagid
• dawakhaad
• calool xanuun
• lulmid

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:

• finan
• maqaarka ama indhaha oo hurdi noqda, xanuun dhinaca midig ee caloosha, lallabbo, matag, saxaro midab khafiif ah leh, kaadida midabka madow

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan jooji qaadashada rilpivirine isla markaana wac dhakhtarkaaga isla markiiba ama aad u hesho daaweyn caafimaad oo degdeg ah:

• finan oo ay weheliso qandho, barar wejiga, bushimaha, afka, carrabka, ama cunaha, nabarro, neefsashada ama wax liqidda oo dhib ah, nabarro afka ah, guduudasho ama indhaha oo barara (conjunctivitis), xanuun dhinaca midig ee aagga caloosha (caloosha), ama kaadi midab madow

Rilpivirine waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog iftiinka, kuleylka badan iyo qoyaanka (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabta jirkaaga ee daawada rilpivirine.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Gacanta ku hayso saad rilpivirine ah. Ha sugin illaa ay kaa dhammaato daawada si aad ugu buuxiso dawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Joogto ah^®
• Juluca^® (sida shey isku dhafan oo ay ku jiraan dolutegravir, rilpivirine)