Ombitasvir, Paritaprevir, Ritonavir, iyo Dasabuvir

Qanacsan

• Kahor qaadashada ombitasvir, paritaprevir, ritonavir, iyo dasabuvir,
• Ombitasvir, paritaprevir, ritonavir, iyo dasabuvir waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, isla markiiba wac dhakhtarkaaga:

Ombitasvir, paritaprevir, ritonavir, iyo dasabuvir hada lagama helo Mareykanka.

Waxaa laga yaabaa inaad horeyba u qaadsiisay cagaarshowga nooca B (fayras ku dhaca beerka wuxuuna sababi karaa waxyeelo daran oo beerka ah) laakiin malaha wax calaamado ah oo cudurka ah. Xaaladdan oo kale, qaadashada iskudhafka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir waxay kordhin kartaa halista in infekshinkaagu uu noqdo mid aad u daran ama nafta halis geliya waxaadna yeelan doontaa calaamado. U sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabtid infekshinka fayraska hepatitis B. Dhakhtarkaagu wuxuu amri doonaa baaritaanka dhiigga si loo arko haddii aad qabto ama aad waligaa qabto cudurka cagaarshowga B. Dhakhtarkaaga ayaa waliba kaa ilaalin doona calaamadaha cudurka cagaarshowga B inta lagu jiro iyo dhowr bilood daaweyntaada ka dib. Haddii loo baahdo, dhakhtarkaagu wuxuu ku siin karaa daawo aad ku daaweyso infekshankan kahor iyo inta lagu jiro daaweyntaada oo ay ku jiraan iskudhafka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir. Haddii aad isku aragto mid ka mid ah astaamaha soo socda inta lagu jiro ama ka dib daaweyntaada, isla markiiba wac dhakhtarkaaga: daal fara badan, maqaarka ama indhaha oo jaale noqda, cunto xumo, lallabbo ama matag, saxaro cirro leh, calool xanuun, ama kaadi madow.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu dalban karaa baaritaano gaar ah kahor, inta lagu jiro, iyo kadib daaweyntaada si loo hubiyo jawaabta jirkaaga ee isku dhafka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir.

Kala hadal dhakhtarkaaga khatarta (yada) qaadashada iskudhafka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir.

Isku darka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir ayaa loo isticmaalaa kaligiis ama marka la isku daro ribavirin (Copegus, Rebetol) si loogu daaweeyo infekshinka cagaarshowga C (ee muddada dheer) (bararka beerka ee uu sababo virus). Ombitasvir waa fayraska cagaarshowga C (HCV) NS5A. Waxay ku shaqeysaa joojinta fayraska keena cagaarshowga C inuu ku faafo jirka. Paritaprevir waa kahortaga difaaca jirka. Waxay ku shaqeysaa iyadoo la dhimayo qaddarka HCV ee jirka ku jira. Ritonavir waa kahortaga difaaca jirka. Waxay ka caawineysaa kordhinta xaddiga daawada 'paritaprevir' ee jirka si daawadu u yeelato saameyn weyn. Dasabuvir waa non-nucleoside NS5B polymerase inhibitor. Waxay ku shaqeysaa iyadoo la dhimayo qaddarka HCV ee jirka ku jira. Lama oga haddii ombitasvir, paritaprevir, ritonavir, ama dasabuvir ay ka hortagaan faafitaanka cagaarshowga C dadka kale.

Isku darka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir waxay u yimaadaan sidii kiniinno afka laga qaato. Dawadani waxay ku timaadaa xirmo 28 maalmood oo dawo ah. Xirmo qaadasho kasta oo maalinle ah waxay leedahay noocyo kiniinno ah oo kala duwan, laba ka kooban isku-darka ombitasvir, paritaprevir, iyo ritonavir iyo laba kale oo ay ku jiraan dasabuvir. Qaado ombitasvir, paritaprevir, iyo ritonavir (2 kiniin) iyo dasabuvir (1 kiniin) subax kasta cuntada, ka dibna qaado dasabuvir (1 kiniin) fiid kasta cuntada. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado ombitasvir, paritaprevir, ritonavir, iyo dasabuvir kudhowaad waqti isku mid ah maalin kasta. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Isku darka ombitasvir, paritaprevir, ritonavir, iyo dasabuvir ayaa xukuma HCV laakiin ma daaweynayo. Sii wad inaad qaadato ombitasvir, paritaprevir, ritonavir, iyo dasabuvir xitaa hadaad fiicantahay. Dhererka daaweyntaada (12 illaa 24 toddobaad) waxay kuxirantahay xaaladaada, sida ugu wanaagsan ee aad uga jawaabeyso daawada, iyo inaad la kulanto waxyeelo daran. Ha u joojin qaadashada ombitasvir, paritaprevir, ritonavir, iyo dasabuvir adigoon dhaqtarkaaga la hadlin.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada ombitasvir, paritaprevir, ritonavir, iyo dasabuvir,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay ombitasvir, paritaprevir, ritonavir, dasabuvir, dawooyin kale oo kasta, ama mid ka mid ah waxyaabaha ku jira ombitasvir, paritaprevir, ritonavir, iyo kiniiniyada dasabuvir. Haddii aad ku yeelatay falcelin halis ah ama nafta halis gelinaysa ritonavir (firiiric, finka ama xoqidda maqaarka), dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan ombitasvir, paritaprevir, ritonavir, iyo dasabuvir. Weydii farmashiistahaaga ama ka hubi Hagaha Daawada liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid alfuzosin (Uroxatral); atorvastatin (Lipitor, Caduet); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol); cisapride (Propulsid; mar dambe lagama heli karo Mareykanka); dronedarone (Multaq); efavirenz (Sustiva, oo ku taal Atripla); daawooyinka ergot-ku jira sida dihydroergotamine mesylate (DHEE 45, Migranal), ergotamine (Ergomar, in Cafergot, in Migergot), iyo methylergonovine (Methergine); ka hortagga uurka ee loo yaqaan 'ethinyl estradiol' sida kaniiniyada qaarkood ('kaniiniyada xakameynta dhalmada'), balastarro, siddooyin siilka hormoonnada hormoonnada ah, iyo waxyaabaha kale ee esthinyl estradiol; everolimus (Afinitor, Zortress); gemfibrozil (Lopid); lovastatin (Altoprev); lurasidone (Latuda); midazolam (afka); phenobarbital; phenytoin (Dilantin, Phenytek); pimozide (Orap); ranolazine (Ranexa); rifampin (Rifadin, Rimactane, gudaha Rifamate, Rifater); sildenafil (Revatio) oo loogu talagalay daaweynta dhiig karka sambabaha; simvastatin (Zocor, oo ku yaal Vytorin); sirolimus (Rapamune); Johannesört wort; tacrolimus (Astagraf XL, Envarsus XR, Prograf); ama triazolam (Halcion). Sidoo kale, u sheeg dhakhtarkaaga haddii aad qaadanayso colchicine (Colcrys, Mitigare) oo aad qabto cudur beerka ama kelyo ah. Dhakhtarkaaga ayaa u badan inuu kuu sheego inaadan qaadan ombitasvir, paritaprevir, ritonavir, iyo dasabuvir haddii aad qaadaneysid mid ama kabadan daawooyinkan.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: alprazolam (Xanax); acetaminophen iyo hydrocodone (Anexsia, Zyfrel); angiotensin receptor blocker (ARB) sida candesartan (Atacand, in Atacand HCT), losartan (Cozaar, in Hyzaar), iyo valsartan (Diovan, in Diovan HCT, Exforge); buprenorphine iyo naloxone (Suboxone, Zubsolv); kaalsiyamka xayiraadaha sida amlodipine (Norvasc, in Caduet), diltiazem (Cardizem, Cartia), nifedipine (Adalat, Afeditab), iyo verapamil (Calan, Verelan); carisoprodol (Soma); cyclobenzaprine (Amrix); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); fluticasone (Flonase, Flovent, Advair); furosemide (Lasix); daawooyinka loogu talagalay garaaca wadnaha aan caadiga ahayn sida amiodarone (Nexterone, Pacerone), bepridil (oo aan hadda laga helin Mareykanka), sibibramram (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), ama quinidine (Nuedexta); ketoconazole; metformin (Glucophage, Riomet); omeprazole (Prilosec); pravastatin (Pravachol); quetiapine (Seroquel); rilpivirine (Edurant; oo dhammeystiran, Odefsey); ritonavir (Norvir, oo ku taal Kaletra) oo loo isticmaalay iskudhafka kahortagayaasha kale ee HIV sida atazanavir (Reyataz), darunavir (Prezista), iyo lopinavir (Kaletra); rosuvastatin (Crestor); salmeterol (Serevent, Advair); iyo voriconazole (Vfend). Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga haddii aad qabtid nooc cudur beer ah oo aan ahayn cagaarshowga C. Dhakhtarkaagu wuxuu kuu sheegi karaa inaadan qaadan ombitasvir, paritaprevir, ritonavir, iyo dasabuvir.
• u sheeg dhakhtarkaaga haddii aad waligaa ku tallaashay beerka, dhiig yaraan (tiro ka yar sidii caadiga ahayd ee unugyada dhiigga cas), ama fayraska difaaca jirka ee dadka (HIV).
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid ombitasvir, paritaprevir, ritonavir, iyo dasabuvir, wac dhakhtarkaaga.
• waa inaad ogaataa in ombitasvir, paritaprevir, ritonavir, iyo dasabuvir ay yareyn karaan waxtarka uur-ka-hortagga uur-qaadidda (kaniiniyada xakameynta dhalmada, balastarrada, faraantiyo, maqaar-galaha, irbado, iyo aaladda intrauterine). Isticmaal nooc kale oo ah xakameynta dhalmada inta aad qaadaneyso ombitasvir, paritaprevir, ritonavir, iyo dasabuvir iyo 2 toddobaad kadib qiyaastaada ugu dambeysa. Kala hadal dhakhtarkaaga noocyada xakameynta dhalmada ee kuu shaqeyn doona inta lagu jiro iyo kadib daaweyntaada ombitasvir, paritaprevir, ritonavir, iyo dasabuvir.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Haddii aad seegto qaddarka ombitasvir, paritaprevir, iyo ritonavir, ku qaado qiyaasta la seegay cuntada sida ugu dhakhsaha badan ee aad u xusuusato. Si kastaba ha noqotee, haddii ay ka badan tahay 12 saacadood tan iyo markii ay ahayd inaad qaadatid qiyaastaada, ka bood qiyaasta la seegay oo sii wad jadwalkaaga qaadashada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Haddii aad seegto qaddarka dasabuvir, ku qaado qiyaasta la seegay cuntada sida ugu dhakhsaha badan ee aad u xusuusato. Si kastaba ha noqotee, haddii ay ka badan tahay 6 saacadood ilaa waqtigii ay ahayd inaad qaadatid qiyaastaada, ka bood qiyaasta la seegay oo sii wad jadwalkaaga qiyaasta daawada ee caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Ombitasvir, paritaprevir, ritonavir, iyo dasabuvir waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• dhibaato xagga hurdada ama hurdada ah

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, isla markiiba wac dhakhtarkaaga:

• finan
• casaan maqaarka
• cuncun
• daciifnimo

Ombitasvir, paritaprevir, ritonavir, iyo dasabuvir ayaa sababi kara waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hayso kartoonka ay soo gashay, si adag u xir, oo ka fog carruurta. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help.Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Viekira Pak^® (sida shey isku dhafan oo ka kooban Ombitasvir, Paritaprevir, Ritonavir, Dasabuvir)