Qoraa: Joan Hall
Taariikhda Abuurista: 2 Febraayo 2021
Taariikhda Cusboonaysiinta: 20 Noofeembar 2024
Anonim
INH and Rifapentine Treatment for LTBI
Dareemoleyad: INH and Rifapentine Treatment for LTBI

Qanacsan

Rifapentine waxaa loo isticmaalaa daawooyin kale si loogu daaweeyo qaaxada firfircoon (TB; infekshan daran oo saameeya sambabaha iyo mararka qaarkood qaybaha kale ee jirka) dadka waaweyn iyo carruurta 12 sano jirka ah ama ka weyn. Rifapentine sidoo kale waxaa loo isticmaalaa isoniazid (Laniazid) si loogu daaweeyo dadka waaweyn iyo carruurta 2 sano jirka ah iyo wixii ka weyn qaaxo (nasasho ama nongrowing), oo ay ku jiraan kuwa ugu dhow dhow dadka qaba qaaxada firfircoon, baaritaanka maqaarka tuberculin wanaagsan, fayraska difaaca jirka (HIV), ama kuwa qaba cudurka sambabka sambabka (nabarrada sambabaha oo aan la garanayn sabab ay u yihiin). Rifapentine wuxuu ku jiraa nooc daawo ah oo loo yaqaan antimycobacterials. Waxay ku shaqeysaa iyada oo la dilayo bakteeriyada keenta infekshinka.

Antibiyootikada sida rifapentine uma shaqeyn doono hargabka, ifilada, ama infekshannada kale ee fayraska keena. Isticmaalka antibiyootikada markii aan loo baahnayn waxay kordhisaa halista aad u qaadi karto jeermis dambe oo iska caabiya daaweynta antibiyootikada.

Rifapentine wuxuu u yimaadaa kiniin afka laga qaato. Marka loo isticmaalo rifapentine-ka in lagu daaweeyo TB-da firfircoon, waxaa badanaa lagu qaataa cuntada laba jeer usbuucii, iyada oo qaadasho ay ugu yaraan 3 maalmood u dhexeyso, labada bilood ee ugu horreysa ka dibna asbuucii hal mar 4 bilood. Marka daawada loo yaqaan 'rifapentine' loo isticmaalo in lagu daaweeyo infekshinka tiibayda ee qarsoon, waa in lagu siiyaa cuntada la qaato toddobaad kasta hal mar. Qaado dawada loo yaqaan 'rifapentine' isla waqtigaas maalin kasta oo la qorsheeyay. Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado rifapentine sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.


Haddii aadan awoodin inaad liqdo kaniiniyada, waad burburin kartaa oo aad ku qasi kartaa daawada qaddar yar oo cunto semisolid ah sida pudding ama tufaax ah. Isku liq isku dar isla markiiba; ha dhigin si aad hadhow u adeegsato.

Sii wad inaad qaadatid dawada loo yaqaan 'rifapentine' ilaa aad ka dhammeysid rijeetada laguu qoray xitaa haddii aad fiicnaan dareento, kana taxaddar inaadan dhaafin qiyaasaha. Haddii aad si dhakhso leh u joojiso qaadashada rifapentine, infekshinkaaga gebi ahaanba lama daaweyn karo waxayna bakteeriyadu u adkeysan kartaa antibiyootikada. Haddii aad seegto qiyaasta daawada 'rifapentine', waxaa laga yaabaa inaad yeelato calaamado aan raaxo lahayn ama halis ah markii aad bilowdo inaad daawada mar labaad qaadatid.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada rifapentine,

  • u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay rifapentine, rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, Rifamate, Rifater), rifaximin (Xifaxan), dawooyin kale oo kasta, ama mid ka mid ah maaddooyinka ku jira kiniiniyada rifapentine. Weydii farmashiistahaaga ama ka hubi Hagaha Daawada liiska waxyaabaha ay ka kooban yihiin.
  • u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: daawooyinka antibiyootikada sida chloramphenicol, ciprofloxacin (Cipro), clarithromycin (Biaxin, in Prevpac), dapsone, iyo doxycycline (Doryx, Monodox, Vibramycin, kuwa kale); daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); antifungals sida fluconazole (Diflucan), itraconazole (Onmel, Sporanox), iyo ketoconazole; kaalsiyamka xayiraadaha sida diltiazem (Cardizem, Taztia, Tiazac, kuwa kale), nifedipine (Adalat, Afeditab, Procardia), iyo verapamil (Calan, Covera, Verelan); clofibrate (Atromid-S; mar dambe lagama heli karo Mareykanka); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); digoxin (Lanoxin); sibibramramide (Norpace); glyburide (Diabeta, Glynase); glipizide (Glucotrol); haloperidol (Haldol); Daawooyinka HIV; levothyroxine (Levoxyl, Synthroid, Tirosint); methadone (Dolophine, Methadose); mexiletine, phenobarbital; phenytoin (Dilantin, Phenytek); prednisone (Rayos); propranolol (Hemangeol, Inderal, InnoPran); quinidine (gudaha Nuedexta), quinine (Qualaquin); sildenafil (Revatio, Viagra); tacrolimus (Astagraf, Envarsus, Prograf); theophylline (Elixophyllin, Theochron, Uniphyl); tocainide (Tonocard; mar dambe lagama heli karo Mareykanka); iyo daawooyinka murugada ee tricyclic-ka sida amitriptyline iyo nortriptyline (Pamelor). Daawooyin kale oo badan ayaa laga yaabaa inay la falgalaan rifapentine, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
  • u sheeg dhakhtarkaaga haddii aad qaadanaysid ama aad isticmaaleysid ka hortagga uurka ee hormoonnada (kaniiniyada ka hortagga uurka, dhejisyo, faraantiyo, maqaar-gelin, iyo irbado). Rifapentine wuxuu yareyn karaa waxtarka uur-qaadidda ee hormoonnada. Waa inaad isticmaashaa hab kale oo xakameynta dhalmada ah inta aad qaadaneysid dawadan. Kala hadal dhakhtarkaaga xakameynta dhalmada inta aad qaadanayso rifapentine.
  • u sheeg dhakhtarkaaga haddii aad qabtid tiibay firfircoon ama haddii aad u jawaabi weyday daawooyinka kale ee tiibayda ama haddii aad qabto ama aad waligaa qabtid cudurka loo yaqaan 'porphyria' (xaalad ay walxaha dabiiciga ah qaarkood ku soo baxaan jirka oo sababi kara calool xanuun, isbeddel ku yimaada fikirka iyo dhaqanka ama astaamo kale), infekshinka HIV, ama cudurka beerka.
  • u sheeg dhakhtarkaaga haddii aad uur leedahay ama aad qorsheyneyso inaad uur yeelato. Haddii aad uur yeelato inta aad qaadanayso rifapentine, wac dhakhtarkaaga.
  • ha nuujin naaska inta aad qaadanaysid rifapentine. Rifapentine wuxuu sababi karaa caanaha naaska inay isu beddelaan casaan-casaan.
  • u sheeg dhakhtarkaaga haddii aad xidhato muraayadaha indhaha oo jilicsan ama ilkaha ilkaha. Rifapentine wuxuu sababi karaa midab casaan joogto ah oo ku dhaca muraayadaha indhaha ama ilkaha ilkaha.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.


Qaado qiyaasta la seegay isla marka aad xasuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaasta xigta, ka bood qiyaasta la seegay oo sii wad jadwalka daawadaada caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Rifapentine wuxuu sababi karaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

  • midab ku meel gaar ah (huruud, casaan guduudan, ama midab bunni ah) maqaarkaaga, ilkaha, candhuufta, kaadida, saxarada, dhididka, iyo ilmada
  • dawakhaad
  • miyir beelid
  • dhidid badan

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:

  • shuban (illaa 2 bilood daaweyntaada ka dib)
  • finan
  • cuncun
  • finan
  • qufac leh xiiq
  • neefsashada oo adkaata
  • indho casaan, cuncun, ama cuncun
  • qandho
  • finanka
  • isbedelka fikirka iyo dhaqanka
  • bararka indhaha, wajiga, dibnaha, carrabka, cunaha, gacmaha, gacmaha, cagaha, anqawyada, ama lugaha hoose
  • garaaca wadnaha oo dhakhso ah ama aan caadi ahayn
  • lallabbo
  • matagid
  • xabad xanuun
  • astaamaha u eg hargabka sida qandho, dhaxan, murqo xanuun, murqo xanuun, daal, iyo madax xanuun
  • calool xanuun
  • cunto xumo
  • kaadi madow
  • kalagoys xanuun ama barar
  • hurdi maqaarka ama indhaha

Rifapentine wuxuu sababi karaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.


Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, iyo meel aysan carruurtu gaarin. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

  • dhiig kaadida ku jira
  • cuncun
  • jir xanuun ama qallafsanaan

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu dalban karaa tijaabooyin shaybaarro qaarkood ah si loo hubiyo jawaabta jirkaaga ee 'rifapentine'.

Kahor baaritaanka shaybaarka, u sheeg dhakhtarkaaga iyo shaqaalaha sheybaarka inaad qaadanayso rifapentine.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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Markii ugu dambeysay ee dib loo eegay - 04/15/2019

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