Cirbadeynta Fosphenytoin

Qanacsan

• Kahor intaadan helin cirbadeynta fosphenytoin,
• Fophenytoin wuxuu sababi karaa kor u kaca sonkorta dhiigaaga. Kala hadal dhakhtarkaaga calaamadaha sonkorta dhiigga oo sarreeya iyo waxa la sameeyo haddii aad calaamadahaas isku aragto.
• Cirbadeynta Fosphenytoin waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:
• Calaamadaha xad dhaafka ah waxaa ka mid noqon kara:

Waxaad la kulmi kartaa cadaadis dhiig oo hooseeya oo halis ah ama nafta halis gelinaya ama garaaca wadnaha oo aan joogto ahayn inta aad qaadanayso cirbadeynta fosphenytoin ama ka dib. U sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa yeelatay wadna garaac aan caadi ahayn ama wadne xannibaad (xaalad aan calaamadaha korantada si caadi ah looga gudbin qolalka sare ee wadnaha loona aadin qolalka hoose). Dhakhtarkaaga ayaa laga yaabaa inuusan rabin inaad hesho cirbadeynta fosphenytoin. Sidoo kale, u sheeg dhakhtarkaaga haddii aad qabtid ama aad waligaa wadnaha istaagtay ama dhiig kar hooseeyo. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba u sheeg dhakhtarkaaga: dawakhaad, daal, garaaca wadnaha oo aan joogto ahayn, ama laab xanuun.

Waxaad ka heli doontaa qiyaas kasta oo ah duritaanka fosphenytoin xarun caafimaad, iyo takhtar ama kalkaaliye caafimaad ayaa kula socon doona si taxaddar leh inta aad qaadaneyso daawada iyo illaa 10 illaa 20 daqiiqo kadib.

Cirbadeynta Fosphenytoin waxaa loo isticmaalaa in lagu daaweeyo suuxdinta guud ee guud ee loo yaqaan 'tonic-clonic suiziz' (oo horey loogu yaqaanay suuxdin weyn, qalal ku lug leh jirka oo dhan) iyo in lagu daaweeyo lagana hortago qallalka bilaaban kara inta lagu jiro ama ka dib qalliinka maskaxda ama nidaamka dareenka. Cirbadeynta Fosphenytoin ayaa sidoo kale loo isticmaali karaa in lagu xakameeyo noocyada suuxdinta ee dadka aan qaadan karin fenytoin afka ah. Fosphenytoin wuxuu ku jiraa fasal dawooyin ah oo loo yaqaan 'anticonvulsants'. Waxay ku shaqeysaa iyadoo hoos loo dhigo dhaqdhaqaaqa korantada ee aan caadiga ahayn ee maskaxda.

Cirbadeynta Fosphenytoin waxay u timaadaa sidii xal (dareere) oo lagu duray xididka (xididka) ama intramuscularly (muruq) dhakhtar ama kalkaaliye caafimaad oo jooga goob caafimaad. Marka fosphenytoin lagu shubo xididada, badanaa waxaa lagu duraa si tartiib ah. Inta jeer ee aad qaadatid cirbadeynta fosphenytoin iyo dhererka daaweyntaadu waxay kuxirantahay sida jirkaagu uga jawaabo daawada. Dhakhtarkaaga ayaa kuu sheegi doona inta jeer ee aad qaadan doontid cirbadeynta fosphenytoin.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin cirbadeynta fosphenytoin,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay fosphenytoin, daawooyinka kale ee hydantoin sida ethotoin (Peganone) ama phenytoin (Dilantin, Phenytek), daawooyin kale oo kasta, ama mid ka mid ah maaddooyinka ku jira cirbadeynta fosphenytoin. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid delavirdine (Rescriptor). Dhakhtarkaagu ma rabi doono inaad hesho cirbadeynta fosphenytoin haddii aad qaadanaysid dawadan.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: albendazole (Albenza); amiodarone (Nexterone, Pacerone); daawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); daawooyinka fangaska sida fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Onmel, Sporanox, Tolsura), miconazole (Oravig), posaconazole (Noxafil), iyo voriconazole (Vfend); fayrasyada qaarkood sida efavirenz (Sustiva, Atripla), indinavir (Crixivan), lopinavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), iyo saquinavir (Invirase); bleomycin; capecitabine (Xeloda); karboplatin; chloramphenicol; chlordiazepoxide (Librium, oo ku taal Librax); daawooyinka kolestaroolka sida atorvastatin (Lipitor, in Caduet), fluvastatin (Lescol), iyo simvastatin (Zocor, in Vytorin); cisplatin; clozapine (Fazaclo, Versacloz); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); diazoxide (Proglycem); digoxin (Lanoxin); sibibramramide (Norpace); disulfiram (Antabuse); doxorubicin (Doxil); doxycycline (Acticlate, Doryx, Monodox, Oracea, Vibramycin); fluorouracil; fluoxetine (Prozac, Sarafem, oo ku taal Symbyax, kuwa kale); fluvoxamine (Luvox); folic acid; fosamprenavir (Lexiva); furosemide (Lasix); H₂ kuwa ka soo horjeedaa sida cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), iyo ranitidine (Zantac); ka hortagga uurka ee hormoonka (kaniiniyada ka hortagga uurka, dhejisyo, giraan, ama irbado); daaweynta beddelka hormoonka (HRT); irinotecan (Camptosar); isoniazid (Laniazid, Rifamate, Rifater); daawooyinka cudurada maskaxda iyo lallabbada; daawooyinka kale ee suuxdinta sida carbamazepine (Carbatrol, Equetro, Tegretol, kuwa kale), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), methsuximide (Celontin), oxcarbazepine (Trilepta, Oxtellar XR, phen) ), iyo valproic acid (Depakene); methadone (Dolophine, Methadose); methotrexate (Otrexup, Rasuvo, Trexall, Xatmep); methylphenidate (Daytrana, Concerta, Metadate, Ritalin); mexiletine; nifedipine (Adalat, Procardia), nimodiwashpine (Nymalize), nisoldipine (Sular); omeprazole (Prilosec); steroids-ka afka laga qaato sida dexamethasone, methylprednisolone (Medrol), prednisolone, iyo prednisone (Rayos); paclitaxel (Abraxane, Taxol); paroxetine (Paxil, Pexeva); praziquantel (Biltricide); quetiapine (Seroquel); quinidine (oo ku taal Nuedexta); keydka; rifampin (Rifadin, Rimactane, gudaha Rifamate, Rifater); salicylate xanuun joojiyeyaasha sida asbiriin, choline magnesium trisalicylate, choline salicylate, diflunisal, magnesium salicylate (Doan’s, kuwa kale), iyo salsalate; sertraline (Zoloft); antibiyootikada sulfa; teniposide; theophylline (Elixophyllin, Theo-24, Theochron); ticlopidine; tolbutamide; trazodone; verapamil (Calan, Verelan, oo ku taal Tarka); vigabatrin (Sabril); iyo fitamiin D. Dhaqtarkaaga waxaa laga yaabaa inuu u baahdo inuu badalo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga waxa ka soo baxa dhirta aad qaadanaysid, gaar ahaan johannesört wort.
• u sheeg dhakhtarkaaga haddii aad waligaa isku aragtay dhibaato beerka ah inta aad qaadanayso cirbadeynta fosphenytoin ama phenytoin. Dhakhtarkaagu ma rabi doono inaad hesho cirbadeynta fosphenytoin.
• u sheeg dhakhtarkaaga haddii aad cabto ama aad waligaa cabto qamri aad u tiro badan. U sheeg dhakhtarkaaga haddii lagaa qaaday baadhitaan shaybaar oo kuu soo sheegay inaad leedahay arrin khatar ah oo laga dhaxlo taas oo ka dhigaysa inay u badan tahay inaad yeelato falcelin maqaar oo daran oo fosphenytoin ah. Sidoo kale, u sheeg dhakhtarkaaga haddii aad qabtid ama waligaa aad qabtid sonkorow, porphyria (xaalad ay walxaha dabiiciga ah qaarkood ku soo baxaan jirka oo ay u keeni karaan calool xanuun, isbeddel ku yimaada fikirka ama dhaqanka, ama calaamado kale), heerarka albumin ee ku yar dhiig, ama kelyo ama beer xanuun.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Kala hadal dhakhtarkaaga hababka xakameynta dhalmada ee wax ku oolka ah ee aad isticmaali karto inta lagu jiro daaweyntaada. Fosphenytoin wuxuu waxyeelleyn karaa uurjiifka.
• haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha in aad qaadanayso cirbadeynta fosphenytoin.
• kala hadal dhakhtarkaaga wixii ku saabsan isticmaalka aaminka ah ee khamriga inta aad qaadanaysid dawadan.
• kala hadal dhakhtarkaaga habka ugu wanaagsan ee loo daryeelo ilkahaaga, ciridkaaga, iyo afkaaga inta lagu guda jiro daaweynta cirbadeynta fosphenytoin. Aad ayey muhiim u tahay inaad si habboon u daryeesho afkaaga si aad u yarayso halista cirridka ee ay keento fosphenytoin.

Fophenytoin wuxuu sababi karaa kor u kaca sonkorta dhiigaaga. Kala hadal dhakhtarkaaga calaamadaha sonkorta dhiigga oo sarreeya iyo waxa la sameeyo haddii aad calaamadahaas isku aragto.

Cirbadeynta Fosphenytoin waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• cuncun, gubasho, ama dareen xanuun
• dhaqdhaqaaqa indhaha oo aan la xakamayn karin
• dhaqdhaqaaqa jirka oo aan caadi ahayn
• luminta isuduwidda
• jahwareer
• dawakhaad
• daciifnimo
• kacsan
• hadal xanaf leh
• afka qalalan
• madax xanuun
• isbeddelo dareenkaaga dhadhanka
• dhibaatooyinka aragga
• dhagaha oo la garaaco ama maqalku ku adkaado
• calool istaag

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda ama kuwa ku taxan qaybta taxaddarrada qaaska ah, isla markiiba wac dhakhtarkaaga:

• barar, midab xumo, ama xanuun meesha la muday ah
• finanka
• finan
• finan
• bararka indhaha, wejiga, cunaha, ama carrabka
• neefsashada ama wax liqidda oo ku adkaata
• xabeeb
• qanjirrada oo barara
• lallabbo
• matagid
• hurdi maqaarka ama indhaha
• xanuun qeybta kore ee midig ee caloosha
• daal fara badan
• nabar ama dhiig bax aan caadi ahayn
• dhibco casaan ama guduud ah oo maqaarka ku yaal
• cunto xumo
• astaamaha hargabka oo kale ah
• qandho, hungur xanuun, finan, boogaha afka, ama nabar nabar fudud, ama wajiga oo barara
• bararka gacmaha, gacmaha, anqawyada, ama lugaha hoose

Cirbadeynta Fosphenytoin waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Qaadashada fosphenytoin waxay kordhin kartaa halista ah inaad ku soo korodho dhibaatooyinka qanjidhadaaga oo ay ku jiraan cudurka Hodgkin (kansar ku bilaabma nidaamka qanjirada). Kala hadal dhakhtarkaaga khataraha isticmaalka daawadan si aad u daaweyso xaaladdaada.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad dhaafka ah waxaa ka mid noqon kara:

• lallabbo
• matagid
• daal
• miyir beelid
• garaaca wadnaha oo aan joogto ahayn
• dhaqdhaqaaqa indhaha oo aan la xakamayn karin
• luminta isuduwidda
• hadal gaabis ah ama gaabis ah
• gariir aan la koontarooli karin qayb ka mid ah jirka

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaaga ayaa laga yaabaa inuu amro tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabtaada ee cirbadeynta fosphenytoin.

Kahor baaritaanka shaybaarka, u sheeg dhakhtarkaaga iyo shaqaalaha sheybaarka inaad qaadanayso cirbadeynta fosphenytoin.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

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