Cirbadaha Cabotegravir iyo Rilpivirine

Qanacsan

• Kahor intaadan helin cirbadaha cabotegravir iyo rilpivirine,
• Cirbadaha Cabotegravir iyo rilpivirine waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan HOW ama qaybaha taxadarka gaarka ah, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo deg deg ah:

Cirbadaha Cabotegravir iyo rilpivirine waxaa loo isticmaalaa isku darka daaweynta cudurka fayraska difaaca jirka ee nooca 1 (HIV-1) ee dadka waaweyn qaarkood. Cabotegravir wuxuu ku jiraa nooc daawooyin ah oo loo yaqaan 'HIV integrase inhibitors'. Rilpivirine waxay ku jirtaa nooc daawooyin ah oo loo yaqaan non-nucleoside reverse transcriptase inhibitors (NNRTIs). Daawooyinkani waxay ku shaqeeyaan hoos u dhigida xaddiga HIV ee dhiiga ku jira. In kasta oo cabotegravir iyo rilpivirine aysan daaweynin HIV, waxay yareyn karaan fursaddaada inaad kuhesho cudurada difaaca jirka (AIDS) iyo cudurada la xiriira HIV sida infekshannada halista ah ama kansarka. Helitaanka daawooyinkan oo ay weheliso ku-dhaqan galmo badbaado leh iyo is-beddello kale oo qaab nololeed ah ayaa yareyn kara halista ah u-qaadista (faafinta) fayraska HIV dadka kale.

Cabotegravir iyo rilpivirine cirbadeynta-sii-deynta (muddada-dheer) cirbadaha waxay u yimaadaan sidii ganaaxyo (dareere) ay ugu durayaan muruq bixiye daryeel caafimaad. Waxaad heli doontaa irbadaha kabotegravir iyo rilpivirine hal mar bil kasta oo lagaa siiyo iyadoo lagaa durayo dawo kasta oo lagaa muday badhidaada.

Kahor intaadan helin irbadahaaga kabotegravir iyo rilpivirine ee fidinta dheer, waa inaad qaadataa cabotegravir (Vocabria) iyo kiniin rilpivirine (Edurant) oo afka ah (afka) hal mar maalintii hal bil (ugu yaraan 28 maalmood) si aad u ogaato inaad u dulqaadan karto kuwan daawooyinka.

Cirbadeynta mudada dheer ee sii-deynta ee loo yaqaan 'Rilpivirine' waxay sababi kartaa falcelinno daran oo daran isla marka la helo cirbada Dhakhtar ama kalkaaliye caafimaad ayaa ku kormeeri doona inta lagu jiro waqtigan si loo hubiyo inaadan dareen-celin daran ku yeelan daawada. Isla markiiba u sheeg dhakhtarkaaga ama kalkaalisada haddii aad isku aragto mid ka mid ah astaamaha soo socda inta lagu jiro ama waxyar ka dib mudistaada: neefsashada oo dhib ah, calool xanuun, dhidid, afka oo kabuubyo, walaac, madax-wareer, madax-wareer, ama wareer.

Cabotegravir iyo irbadaha sii kordhaya ee rilpivirine waxay sii caawinayaan xakameynta HIV, laakiin ma daaweynayaan. Hayso dhammaan ballamaha si aad u hesho irbadaha kabtegravir iyo rilpivirine ee sii-daynta xitaa haddii aad caafimaad qabtid. Haddii aad seegto ballamaha si aad u hesho cirbadaha fiditaanka cabotegravir iyo rilpivirine, xaaladdaadu way sii adkaan doontaa in la daweeyo.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin cirbadaha cabotegravir iyo rilpivirine,

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay cabotegravir, rilpivirine, daawooyin kale, ama mid ka mid ah waxyaabaha ku jira kabotegravir iyo irbadaha rilpivirine. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga haddii aad qaadanaysid carbamazepine (Epitol, Equetro, Tegretol), dexamethasone (Decadron), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rimane Rifater), rifapentine (Priftin), ama johannesört St. Dhakhtarkaaga ayaa u badan inuu kuu sheego inaadan qaadan irbadaha cabotegravir iyo rilpivirine haddii aad qaadanaysid mid ama kabadan dawooyinkan.
• u sheeg dhakhtarkaaga iyo farmashiistaha waxa kale ee dhakhtar qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: amiodarone (Nexterone, Pacerone); anagrelide (Agrylin); azithromycin (Zithromax); chloroquine; chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram (Celexa); clarithromycin (Biaxin); dofetilide (Tikosyn); donepezil (Aricept); erythromycin (E-Mycin, Eryc, Ery-Tab, PCE); flecainide (Tambocor); fluconazole (Diflucan); haloperidol (Haldol); dawooyin kale oo lagu daaweeyo HIV / AIDS; ibutilide (Corvert); levofloxacin; methadone (Dolophine); moxifloxacin (Velox); ondansetron (Zuplenz, Zofran); dawooyinka kale ee NNRTIs ee lagu daaweeyo HIV / AIDS; pentamidine (NebuPent, Pentam); pimozide (Orap); procainamide; quinidine (oo ku taal Nuedexta); sotalol (Betapace, Sorine, Sotylize); iyo thioridazine. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale laga yaabaa inay la falgalaan cabotegravir iyo rilpivirine, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa isku buuqday ama cudurro kale oo maskaxda ah, ama cudur beerka ah, oo ay ku jiraan infakshanka cagaarshowga B ama C.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanayso cirbadaha cabotegravir iyo rilpivirine, wac dhakhtarkaaga. Waa inaadan naas nuujin haddii aad qabtid HIV ama haddii aad qaadanayso cirbadaha cabotegravir iyo rilpivirine.
• waa inaad ogaataa in cirbadaha kabotegravir iyo rilpivirine ay sababi karaan isbadal fikirkaaga, dhaqankaaga, ama caafimaadka maskaxda. Isla markiiba wac dhakhtarkaaga haddii aad isku aragto mid ka mid ah astaamaha soo socda inta aad qaadanaysid iyo cirbadaha rilpivirine: niyad jab cusub ama ka sii daraysa; ama aad ka fikirto inaad is disho ama aad qorsheysato ama aad isku daydo inaad sidaas sameyso. Hubso in qoyskaagu ogyahay astaamaha halista ah si ay ugu wici karaan dhakhtarkaaga haddii aadan awoodin inaad keligaa daaweyn raadsato.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Haddii aad seegto ballan kabategravir iyo rilpivirine ah in ka badan 7 maalmood, wac dhakhtarkaaga isla markiiba si aad ugala hadasho xulashooyinkaaga daaweyn.

Cirbadaha Cabotegravir iyo rilpivirine waxay sababi karaan waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• xanuun, damqasho, barar, casaan, cuncun, nabar, ama diirimaad goobta duritaanka
• qandho
• daallan
• madax xanuun
• muruq, laf, ama dhabar xanuun
• lallabbo
• dhibaato xagga hurdada ama hurdada ah
• dawakhaad
• miisaanka oo kordha

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan HOW ama qaybaha taxadarka gaarka ah, wac dhakhtarkaaga isla markiiba ama u hesho daaweyn caafimaad oo deg deg ah:

• finan leh ama aan lahayn: qandho; daal; murqaha ama kalagoysyada xanuunka; barar wejiga, dibnaha, afka, carrabka, ama cunaha; finanka maqaarka; neefsashada ama liqidda oo ku adkaata; nabarrada afka; guduudasho ama barar indhaha; xanuun dhinaca midig ee caloosha; saxaro cirro leh; lallabbo matagid; ama kaadi midab madow ah
• indhaha jaalaha ah ama maqaarka; caloosha xanuun midigta sare; nabar; dhiig bax; cunto xumo; jahwareer; kaadi kaadi huruud ah ama midab bunni ah leh; ama saxaro cirro leh

Cirbadaha Cabotegravir iyo rilpivirine waxay sababi karaan waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn inta aad qaadanaysid daawooyinkan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabta jirkaaga ee cirbadaha cabotegravir iyo rilpivirine.

Weydii farmasiilahaaga wixii su'aalo ah ee aad ka qabtid irbadaha cabotegravir iyo rilpivirine.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Cabenuva^®