Cirbadeynta Granisetron

Qanacsan

• Kahor intaadan isticmaalin duritaanka granisetron,
• Cirbadeynta Granisetron waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, wac takhtarkaaga isla markiiba ama raadso daaweyn caafimaad oo degdeg ah:
• Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

Cirbadeynta isla markiiba-Granisetron waxaa loo isticmaalaa in looga hortago lallabbo iyo matag ay keento kansarka kiimikada iyo in looga hortago lana daaweeyo lallabbo iyo matag dhici kara qalliinka ka dib. Cirbadeynta mudada dheer ee sii-deynta ee 'Granisetron' waxaa loo isticmaalaa daawooyin kale si looga hortago lallabbo iyo matag ay keento kansarka kiimoterapi kaas oo dhici kara isla markiiba ama dhowr maalmood ka dib marka la qaato daawooyinka kemotherabi. Granisetron wuxuu ku jiraa nooc daawo ah oo loo yaqaan 5-HT₃ antagonistayaasha soo dhaweynta. Waxay ku shaqeysaa iyadoo laga horjoogsanayo serotonin, shey dabiici ah oo jirka ku jira oo keena lallabbo iyo matag.

Cirbadeynta-sii-deynta degdegga ah ee Granisetron waxay u timaaddaa sidii xalka (dareeraha) lagu duray xididka (xididka) xididka dheecaanka fiditaanka-dheerna wuxuu u yimaadaa dareere si hoose loogu duray (maqaarka hoostiisa). Si looga hortago lallabbo iyo matag ay keento kiimiko ku daaweynta kiimikada, granisetron-sii-deynta degdegga ah iyo cirbadeynta sii-fidinta ah waxaa badanaa bixiya bixiye daryeel caafimaad isbitaal ama rug caafimaad 30 daqiiqo gudahood ka hor bilawga daaweynta kemotherabi. Si looga hortago lallabbo iyo matag qalliin sababay, granisetron isla markiiba-sii-deynta ayaa badanaa la siiyaa inta lagu jiro qalliinka. Si loo daaweeyo lallabbo iyo matag qalliin sababay, granisetron waxaa la siiyaa isla marka uu lallabbo iyo mataggu dhaco.

Weydii farmashiistahaaga ama dhakhtarkaaga nuqul ka mid ah macluumaadka soo saaraha ee bukaanka.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan isticmaalin duritaanka granisetron,

• u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay granisetron, alosetron (Lotronex), dolasetron (Anzemet), ondansetron (Zofran, Zuplenz), palonosetron (Aloxi, in Akynzeo), dawooyin kale oo kasta, ama mid ka mid ah maaddooyinka ku jira duritaanka granisetron Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: amiodarone (Cordarone, Nexterone, Pacerone); azithromycin (Zithromax), chlorpromazine, citalopram (Celexa); clarithromycin (Biaxin, gudaha Prevpac); erythromycin (E.E.S., ERYC, Erythrocin, kuwa kale); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Subsys); ketoconazole (Nizoral); lithium (Lithobid); daawooyinka dhibaatooyinka wadnaha; daawooyinka lagu daaweeyo xanuunka dhanjafka sida almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), iyo zolmitriptan (Zomig); mirtazapine (Remeron); monoamine oxidase (MAO) inhibitors ay ka mid yihiin isocarboxazid (Marplan), methylene blue; linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), iyo tranylcypromine (Parnate); moxifloxacin (Avelox); pimozide (Orap); phenobarbital; Xakamaynta serotonin reuptake inhibitors (SSRIs) sida citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax, kuwa kale), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertral) ; serotonin-norepinephrine reuptake inhibitors (SNRI) daawooyinka desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), iyo venlafaxine; sotalol (Betapace, Sorine); thioridazine; iyo tramadol (Conzip, Ultram, oo ku taal Ultracet). Haddii aad qaadanayso cirbadeynta sii-dhererka-dheer, sidoo kale u sheeg dhakhtarkaaga haddii aad qaadanaysid dawooyinka xinjirowga lidka ku ah ('khafiifiyeyaasha dhiigga') sida warfarin (Coumadin, Jantoven); dawooyinka antiplatelet sida cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox), prasugrel (Effient), ama ticlopidine. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca. Daawooyin kale oo badan ayaa sidoo kale la macaamili kara granisetron, markaa hubi inaad u sheegto dhakhtarkaaga dhammaan daawooyinka aad qaadanaysid, xitaa kuwa aan ka muuqan liiskan.
• u sheeg dhakhtarkaaga haddii dhawaan lagugu qalay caloosha ama calool fadhido. Sidoo kale, u sheeg dhakhtarkaaga haddii adiga ama qof kale oo qoyskaaga ka mid ahi uu leeyahay ama uu waligiis soo maray QT syndrome (xaalad kordhinaysa halista ah inuu ku dhaco wadno garaac aan caadi ahayn oo u horseedi kara miyir beelid ama dhimasho lama filaan ah), nooc kale oo wadno-garaac aan caadi ahayn ama dhibaato wadnaha ah, isu dheelitir la'aanta elektroolka, ama kalyaha ama wadno xanuun.
• u sheeg dhakhtarkaaga haddii aad uur leedahay, qorsheyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato intaad isticmaaleyso duritaanka granisetron, wac dhakhtarkaaga.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Cirbadeynta Granisetron waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• madax xanuun
• calool istaag
• dhibaato xagga hurdada ama hurdada ah

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamaha soo socda, wac takhtarkaaga isla markiiba ama raadso daaweyn caafimaad oo degdeg ah:

• finan
• finan
• dhaqid
• cuncun
• neefsashada ama wax liqidda oo ku adkaata
• neefta oo ku qabata
• bararka indhaha, wejiga, afka, carrabka, ama cunaha
• xabad xanuun
• guduudasho, barar, ama diirimaad qandho leh ama aan lahayn (duritaanka sii-fidinta)
• dhiig ciribtiran goobta duritaanka, nabar, ama xanuun (cirbadeynta sii-fidinta)
• calool xanuun ama barar
• dawakhaad, madax-wareer, iyo suuxdin
• isbedelada garaaca wadnaha
• kacsan, dhalanteed (aragtida wax ama maqalka codad aan jirin). isbedelada xaalada maskaxda, ama miyir beel (miyir beelid)
• gariir, luminta isku-duwidda, ama murqaha oo adkaada ama foorara
• qandho
• dhidid badan
• jahwareer
• lallabbo, matag, iyo shuban
• qalal

Cirbadeynta Granisetron waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn intaad isticmaaleyso daawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

• madax xanuun

Dhammaan ballamaha la dhig dhakhtarkaaga.

Kahor baaritaanka shaybaarka (gaar ahaan kuwa ku lugta leh methylene buluug), u sheeg dhakhtarkaaga iyo shaqaalaha sheybaarka inaad qaadanayso cirbadeynta granisetron.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Sustol^®