Cirbadda Trastuzumab

Qanacsan

• Kahor intaadan helin sheyga la isku duro ee 'trastuzumab',
• Cirbadda Trastuzumab waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:
• Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, isla markiiba wac dhakhtarkaaga:

Cirbadeynta Trastuzumab, cirbadeynta trastuzumab-anns, cirbadeynta trastuzumab-dkst, iyo cirbadeynta trastuzumab-qyyp waa daawooyinka bayoolaji (daawooyinka laga sameeyay noolaha nool). Cirbadeynta Biosimilar trastuzumab-anns, cirbadeynta trastuzumab-dkst, iyo cirbadeynta trastuzumab-qyyp waxay aad ugu egyihiin cirbadeynta trastuzumab waxayna u shaqeeyaan si la mid ah cirbadda trastuzumab ee jirka. Sidaa darteed, ereyga alaabada la isku duro trastuzumab ayaa loo isticmaali doonaa in lagu matalo daawooyinkan doodan.

Waxyaalaha la isku duro ee Trastuzumab waxay sababi kartaa dhibaatooyin wadnaha oo halis ah ama naf-gooya. U sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabtid cudur wadne. Dhakhtarkaagu wuxuu amri doonaa baaritaano kahor iyo inta daaweyntaadu socoto si loo arko haddii wadnahaagu si fiican u shaqeynayo oo kugu filan si aad si badbaado leh ugu hesho badeecada cirbadeynta trastuzumab. U sheeg dhakhtarkaaga iyo farmashiistahaaga haddii lagaa daweynayo shucaaca laabtaada ama daawada anthracycline ee kansarka sida daunorubicin (Daunoxome, Cerubidine), doxorubicin (Doxil), epirubicin (Ellence), iyo idarubicin (Idamycin). Haddii aad isku aragto mid ka mid ah astaamaha soo socda, isla markiiba wac dhakhtarkaaga: qufac; neefta oo ku qabata; bararka gacmaha, gacmaha, cagaha, anqawyada ama lugaha hoose; miisaanka oo kordha (in ka badan 5 rodol [qiyaastii 2.3 kiilogaraam] 24 saac gudahood); dawakhaad; miyir beelid; ama dhakhso, aan caadi ahayn, ama garaaca wadnaha.

Waxyaalaha la isku duro ee 'Trastuzumab' waxay sababi kartaa falcelinno halis ah ama nolosha halis geliya oo dhici kara inta daawada la siinayo ama ilaa 24 saacadood ka dib. Waxyaalaha la isku duro ee Trastuzumab ayaa sidoo kale sababi kara waxyeelo daran oo sambabka ah. U sheeg dhakhtarkaaga haddii aad qabto ama aad waligaa qabto cudur sambabaha ah ama haddii aad buro ku leedahay sanbabadaada, gaar ahaan haddii ay kugu keentay neefsashada oo kugu adkaata. Dhakhtarkaaga ayaa si taxaddar leh kuu ilaalin doona marka lagu siiyo badeecada la isku duro ee 'trastuzumab' si markaas ay daaweyntaadu u carqaladeyso haddii aad la kulanto fal-celin daran Haddii aad leedahay mid ka mid ah astaamaha soo socda, isla markiiba u sheeg dhakhtarkaaga: qandho, qarqaryo, lallabbo, matag, xanuun, madax xanuun, wareer, daciifnimo, firiiric, finan, cuncun, cidhiidhi cunaha; ama dhibaato neefsashada ama wax liqidda.

U sheeg dhakhtarkaaga haddii aad uur leedahay ama aad qorsheyneyso inaad uur yeelato. Waxyaalaha la isku duro ee Trastuzumab ayaa waxyeello u geysan kara ilmahaaga aan dhalan. Waa inaad isticmaashaa ka hortagga uurka si aad uga hortagto uur inta lagu jiro daaweyntaada iyo 7 bilood ka dib qiyaastaada ugu dambeysa. Kala hadal dhakhtarkaaga hababka xakameynta dhalmada ee adiga kuu shaqeyn doona. Haddii aad uur yeelato inta lagu guda jiro daaweyntaada alaabada irbadda trastuzumab, isla markiiba wac dhakhtarkaaga.

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa baaritaano gaar ah si loo hubiyo jawaabta jirkaaga ee alaabada irbadda trastuzumab.

Kala hadal dhakhtarkaaga khataraha ka dhalan kara qaadashada alaabta la isku duro ee 'trastuzumab'.

Waxyaalaha la isku duro ee Trastuzumab waxaa loo isticmaalaa dawooyin kale ama ka dib marka daawooyin kale loo isticmaalo daaweynta nooc ka mid ah kansarka naasaha oo ku faafay qaybaha kale ee jidhka. Waxyaalaha la isku duro ee Trastuzumab ayaa sidoo kale la isticmaalaa inta lagu jiro iyo kadib daaweynta daawooyinka kale si loo yareeyo fursada nooc ka mid ah kansarka naasaha ku soo laaban karo. Waxyaalaha la isku duro ee Trastuzumab ayaa sidoo kale loo isticmaalaa dawooyin kale oo lagu daaweeyo noocyo ka mid ah kansarka caloosha oo ku faafay qaybaha kale ee jidhka. Trastuzumab waxay ku jirtaa nooc daawooyin ah oo loo yaqaan monoclonal antibodies. Waxay ku shaqeysaa joojinta koritaanka unugyada kansarka.

Waxyaalaha la isku duro ee Trastuzumab waxay u yimaadaan sidii dareere ama budo oo kale oo lagu qaso dareeraha si dhakhtar ama kalkaaliye caafimaad ay ugu mudayaan xididka. Marka sheyga la isku duro ee loo yaqaan 'trastuzumab' loo isticmaalo in lagu daaweeyo kansarka naasaha ee faafay, badiyaa waxaa la siiyaa toddobaadkii hal mar. Marka alaabada la isku duro ee loo yaqaan 'trastuzumab duray' loo isticmaalo in looga hortago soo noqoshada kansarka naasaha, badanaa waxaa la siiyaa usbuucii hal mar inta lagu jiro daweynta dawooyinka kale ee kiimoteraabiga ah, ka dibna hal mar 3dii toddobaadba mar ka dib daaweynta daawooyinka kale ayaa la dhammaystiraa illaa 52 toddobaad. Marka sheyga la isku duro ee 'trastuzumab' loo isticmaalo in lagu daaweeyo kansarka caloosha, badanaa waxaa la siiyaa hal mar 3dii toddobaadba mar. Dhererka daaweyntaadu waxay kuxirantahay sida ugu wanaagsan ee jirkaaga uga jawaab celiyo daawada iyo dhibaatooyinka soo raaca.

Daawadan waxaa loo qori karaa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor intaadan helin sheyga la isku duro ee 'trastuzumab',

• u sheeg dhakhtarkaaga iyo farmashiistahaaga haddii aad xasaasiyad ku leedahay trastuzumab, trastuzumab-anns, trastuzumab-dkst, dawooyinka trastuzumab-qyyp oo laga sameeyay shiinaha borotiinka unugyada ugxan sidaha, dawooyinka kale, ama aalkolada benzyl. Weydii farmashiistahaaga haddii aadan hubin in daawo aad xasaasiyad u leedahay laga sameeyay Shiinaha borotiinka unugyada ugxan sidaha ama inuu ku jiro aalkolada benzyl
• u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Dhakhtarkaaga ayaa laga yaabaa inuu u baahdo inuu beddelo qiyaasta daawooyinkaaga ama uu si taxaddar leh kuugu ilaaliyo dhibaatooyinka soo raaca.
• u sheeg dhakhtarkaaga haddii aad leedahay ama aad waligaa dareentay mid ka mid ah xaaladaha lagu xusay qaybta DIGNIIN MUHIIM AH ama xaalad kale oo caafimaad.
• u sheeg dhakhtarkaaga haddii aad naas nuujinayso.
• haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha in aad qaadanayso alaabada irbadda trastuzumab.

Ilaa dhakhtarkaagu kuu sheego mooyee, sii wad cuntadaada caadiga ah.

Wac dhakhtarkaaga isla markiiba haddii aadan awoodin inaad ilaaliso balan si aad u hesho qadar ah sheyga duritaanka trastuzumab.

Cirbadda Trastuzumab waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

• shuban
• calool istaag
• calool xanuun
• laabjeex
• cunto xumo
• dhabarka, lafta, kalagoysyada, ama muruq xanuun
• dhibaato xagga hurdada ama hurdada ah
• olol kulul
• kabuubyo, gubasho, ama xoqitaan gacmaha, gacmaha, cagaha, ama lugaha
• isbeddelka muuqaalka ciddiyaha
• finanka
• niyad jab

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan ama kuwa ku taxan qaybta DIGNIIN MUHIIM AH, isla markiiba wac dhakhtarkaaga:

• cuna xanuun, qandho, dhaxan, kaadida oo ku adkaata, kaadida oo xanuunta, iyo calaamadaha kale ee cudurka
• dheecaanka sanka iyo nabaro kale ama dhiig bax aan caadi ahayn
• daal fara badan
• maqaarka cirro leh
• lallabbo matagid; cunto xumo; daal; garaaca wadnaha oo degdeg ah; kaadi madow; xaddiga kaadida; calool xanuun; suuxdinta; dhalanteed; ama murqo xanuun iyo dabac

Cirbadda Trastuzumab waxay sababi kartaa waxyeelo kale. Wac dhakhtarkaaga haddii aad qabtid dhibaatooyin aan caadi ahayn inta aad qaadanaysid dawadan.

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Dhakhtarkaagu wuxuu dalban karaa tijaabooyin shaybaarro qaarkood ah si loo hubiyo jawaabta jirkaaga ee duritaanka trastuzumab.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

• Herceptin^® (trastuzumab)
• Kanjinti^® (trastuzumab-anns)
• Ogivri^® (trastuzumab-dkst)
• Trazimera^®(trastuzumab-qyyp)