Silsilado Iftiin Bilaash ah

Qanacsan

• Waa maxay tijaabada silsiladaha iftiinka bilaashka ah?
• Maxaa loo adeegsadaa?
• Maxaan ugu baahanahay tijaabada silsiladaha iftiinka bilaashka ah?
• Maxaa dhacaya inta lagu jiro tijaabada silsiladaha iftiinka bilaashka ah?
• Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
• Ma jiraan wax khatar ah oo ka iman kara tijaabada silsiladaha iftiinka bilaashka ah?
• Maxay natiijooyinka ka dhigan yihiin?
• Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka silsiladaha iftiinka bilaashka ah?
• Tixraacyo

Waa maxay tijaabada silsiladaha iftiinka bilaashka ah?

Silsiladaha fudfudud waa borotiino ay sameeyeen unugyada plasma, nooc ka mid ah unugyada dhiiga cad. Unugyada plasma waxay kaloo sameeyaan immunoglobulin (antibodies). Immunoglobulins wuxuu caawiyaa jirka inuu ka difaaco jirro iyo infekshanno. Immunoglobulins-ka waxaa la sameeyaa marka silsiladaha fudud ay ku xirmaan silsilado culus, nooc kale oo borotiin ah. Marka silsiladaha fudud ay ku xirmaan silsilado culus, waxaa loo yaqaanaa xidhan silsilado fudud.

Caadi ahaan, unugyada plasma waxay sameeyaan qadar yar oo silsilado fudud ah oo aan ku xidhnayn silsilado culus. Waxay taa badalkeeda loo sii daayaa dhiiga. Silsiladahan aan xirnayn ayaa loo yaqaan bilaash ah silsilado fudud.

Waxaa jira laba nooc oo silsilado khafiif ah: lambda iyo silsilado fudud. Tijaabooyinka silsiladaha iftiinka bilaashka ah ayaa lagu cabiraa qadarka lambda iyo silsiladaha iftiinka bilaashka ah ee dhiigga ku jira. Haddii xaddiga silsiladaha nalka ee bilaashka ah ay ka sarreeyaan ama ka hooseeyaan sida caadiga ah, waxay macnaheedu noqon kartaa inaad leedahay cillad unugyada dhiigga. Kuwaas waxaa ka mid ah myeloma badan, kansar ku dhaca unugyada plasma, iyo amyloidosis, xaalad sababa isku-uruurinta halista ah ee borotiinka ee xubnaha iyo unugyada kala duwan.

Magacyada kale: Kappa / lambda ratio lacag la'aan ah, kappa / lambda nalka bilaashka ah ee bilaashka ah, freelite, kappa iyo lambda silsiladaha iftiinka ee bilaashka ah, silsiladaha iftiinka ee bilaashka ah ee immunoglobulin

Maxaa loo adeegsadaa?

Tijaabada silsiladaha iftiinka bilaashka ah ayaa loo isticmaalaa in lagu caawiyo baaritaanka ama la socoshada ciladaha unugyada plasma.

Maxaan ugu baahanahay tijaabada silsiladaha iftiinka bilaashka ah?

Waxaad u baahan kartaa baaritaankaan haddii aad isku aragto astaamaha ciladda unugyada dhiigga. Waxay kuxirantahay cilladda plasma ee aad yeelan karto iyo xubnaha ay saameyso, astaamahaaga waxaa ka mid noqon kara:

• Lafa xanuun
• Daal
• Kabuubyo ama ruxruxasho gacmaha iyo lugaha
• Carrab barar
• Dhibco guduudan oo maqaarka ah

Maxaa dhacaya inta lagu jiro tijaabada silsiladaha iftiinka bilaashka ah?

Xirfadlaha daryeelka caafimaadka ayaa tijaabo dhiig ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.

Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?

Uma baahnid wax diyaargarow gaar ah oo loogu talagalay tijaabada silsiladaha iftiinka bilaashka ah.

Ma jiraan wax khatar ah oo ka iman kara tijaabada silsiladaha iftiinka bilaashka ah?

Khatar aad u yar baa jirta in dhiig lagaa qaado. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan.

Maxay natiijooyinka ka dhigan yihiin?

Natiijooyinkaaga ayaa tusi doona qaddarka silsiladaha iftiinka lambda ee lambda iyo kappa. Waxay sidoo kale bixin doontaa isbarbardhig u dhexeeya labada. Haddii natiijooyinkaagu aysan caadi ahayn, waxaa laga yaabaa inay ka dhigan tahay inaad qabto cillad unugyada dhiigga, sida:

• Myeloma badan
• Amyloidosis
• MGUS (monoclonal gammopathy oo ahmiyad aan la garanayn). Tani waa xaalad aad ku leedahay heerar borotiin aan caadi ahayn. Badanaa wax dhibaato ah ama astaamo ah ma keento, laakiin mararka qaarkood waxay isu beddeshaa myeloma badan.
• Waldenstrom macroglobulinemia (WM), kansar ku dhaca unugyada dhiiga cad. Waa nooc ka mid ah qanjidhada aan Hodgkin ahayn.

Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.

Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka silsiladaha iftiinka bilaashka ah?

Tijaabada silsiladaha iftiinka bilaashka ah badanaa waxaa lagu dalbadaa baaritaano kale, oo ay kujirto baaritaanka dhiigga ee difaaca jirka, si looga caawiyo xaqiijinta ama meesha looga saaro ogaanshaha cudurka.

Tixraacyo

1. Bulshada Kansarka Mareykanka [Internet]. Atlanta: American Cancer Society Inc.; c2019. Tijaabooyinka Lagu Sameeyo Myeloma Badan; [cusboonaysiiyay 2018 Feb 28; daliishaday 2019 Dec 21]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/testing.html
2. Bulshada Kansarka Mareykanka [Internet]. Atlanta: American Cancer Society Inc.; c2019. Waa maxay Waldenstrom Macroglobulinemia ?; [cusbooneysiiyay 2018 Jul 29; daliishaday 2019 Dec 21]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.cancer.org/cancer/waldenstrom-macroglobulinemia/about/what-is-wm.html
3. Bulshada Mareykanka ee Cudurka Cudurka Hematology [Internet]. Washington DC: Bulshada Mareykanka ee Cudurka Cudurka Hematology; c2019. Myeloma; [daliishaday 2019 Dec 21]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.hematology.org/Patients/Cancers/Myeloma.aspx
4. International Myeloma Foundation [Internet]. Waqooyiga Hollywood (CA): International Myeloma Foundation; Fahmitaanka Freelite iyo Hevylite Tests; [daliishaday 2019 Dec 21]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.myeloma.org/sites/default/files/resource/u-freelite_hevylite.pdf
5. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington DC: Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2019. Silsilado iftiin la'aan ah; [cusboonaysiiyay 2019 Oct 24; daliishaday 2019 Dec 21]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/serum-free-light-chains
6. Mayo Clinic [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2019. Gammopathy Monoclonal oo ahmiyad aan la cayimin (MGUS): Calaamadaha iyo sababaha; 2019 Meey 21; [daliishaday 2019 Dec 21]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.mayoclinic.org/diseases-conditions/mgus/symptoms-causes/syc-20352362
7. Mayo Clinic: Mayo Laboratories [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1995–2019. Aqoonsiga Tijaabada: FLCP: Silsiladaha Nuurka Bilaashka ah ee 'Immunoglobulin', Seer: Daaweyn iyo Fasiraad; [daliishaday 2019 Dec 21; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/84190
8. Machadka Kansarka Qaranka [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka Plasma Cell Neoplasms (oo ay kujirto Myeloma badan) Daaweynta (PDQ®) –Bogga Bukaanka; [cusboonaysiiyay 2019 Nofeembar 8; daliishaday 2019 Dec 21]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq
9. Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Tijaabooyinka Dhiigga; [daliishaday 2019 Dec 21]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/blood-tests
10. Jaamacadda Rochester Medical Center [Internet]. Rochester (NY): Jaamacadda Rochester Medical Center; c2019. Caafimaadka Encyclopedia: Silsiladaha Nalka Bilaashka ah (Dhiigga); [daliishaday 2019 Dec 21]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=serum_free_light_chains

Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.