Wax kasta oo aad u baahan tahay inaad ka ogaato Tallaalka COVID-19 ee Johnson & Johnson

Qanacsan

• Sidee buu u shaqeeyaa tallaalka Johnson & Johnson COVID-19?
• Sidee ayuu waxtar u leeyahay tallaalka Johnson & Johnson COVID-19?
• Xanuunka COVID-19 ee daran iyo Xogta Dhimashada
• Noocyada COVID-19
• Immisa qiyaasood oo ah tallaalka Johnson & Johnson COVID-19 ayaad u baahan tahay?
• Sidee buu tallaalka Johnson & Johnson u saameeya gudbinta COVID-19?
• Dib u eegis loogu talagalay

Bishii Febraayo 26, guddiga latalinta tallaalka ee FDA ayaa si wada jir ah ugu codeeyay inay ku taliyaan tallaalka Johnson & Johnson ee COVID-19 si loogu isticmaalo degdeg ah. Taasi micnaheedu waa tallaalka - oo u baahan hal qiyaas oo keliya - ayaa diyaar u noqon kara in laga isticmaalo Maraykanka dhammaadka Maarso, sida ay sheegtay Xarunta Cilmi -baarista iyo Siyaasadda Cudurrada Cudurrada (CIDRAP).

Laakiin, sidee bay waxtar u leedahay tallaalka Johnson & Johnson ee COVID-19? Oo sidee bay u barbar dhigtaa tallaalada kale ee COVID-19 ee Pfizer iyo Moderna? Waa kuwan waxa aad u baahan tahay inaad ogaato.

Sidee buu u shaqeeyaa tallaalka Johnson & Johnson COVID-19?

Haddii aad taqaanid tallaallada COVID-19 ee ay abuureen Pfizer iyo Moderna, markaa waxaad u badan tahay inaad ogtahay inay labaduba yihiin tallaallada mRNA. Taasi waxay ka dhigan tahay inay ku shaqaynayaan codaynta qayb ka mid ah fayraska SARS-CoV-2 ee borotiinka laf-dhabarta ah (qaybta fayraska ee isku dhejisa unugyada jidhkaaga) iyo adeegsiga qaybahaas ku-qoran si aad uga kiciso jawaab-celin jidhkaaga ah si ay u abuurto unugyada difaaca jirka ee fayraska. (Fiiri: Sidee ayuu waxtar u leeyahay tallaalka COVID-19?)

Tallaalka Johnson & Johnson si yar ayuu u shaqeeyaa. Hal shay, ma aha tallaal mRNA. Waa tallaal adenovector, taas oo macnaheedu yahay inay adeegsato fayras aan firfircoonayn (kiiskan, adenovirus, oo sababa hargabka caadiga ah) sida vektor si uu u keeno borotiinka (kiiskan, borotiinka kororka ee SARS-CoV-2) oo jirkaagu u aqoonso inay khatar tahay oo samee unugyada difaaca jirka, ayay tiri Brittany Busse, MD, agaasimaha caafimaadka ee WorkCare.

Hadda, waxaa laga yaabaa inaad la yaabto haddii "fayras aan dhaq-dhaqaaq lahayn" oo jirkaaga la geliyo uu si badheedh ah kuu bukoon doono, laakiin ma dhici doonto. “Fayras aan nooleynin kuma tarmi karo ama kuuma keeni karo inaad xanuunsato,” ayay tiri Abisola Olulade, MD, oo ah dhakhtar dawo qoyska ka tirsan oo ka tirsan Sharp Rees-Stealy Medical Group. Halkii, adenovirus-ka tallaalka Johnson & Johnson ee COVID-19 wuxuu si fudud ugu adeegaa sida side (ama “vector”) hidda-wadaha borotiinnada SARS-CoV-2 ee unugyadaada, taasoo keenta in unugyadu nuqullo ka sameeyaan hidda-wadahaas, ayay sharraxday. Ka feker hidda-wadaha borotiinka kororka sida tilmaamo loogu talagalay sida jidhkaagu ula dagaallami karo SARS-CoV-2, ayuu raaciyay Dr. Olulade. "Borotiinkaan soo kordhay waxaa aqoonsan kara nidaamkaaga difaaca waxayna kuu horseedi karaan inaad abuurto unugyada difaaca jirka oo ka ilaalin doona COVID," ayay tiri. (FYI: Tallaalka hargabku wuxuu u shaqeeyaa si la mid ah.)

In kasta oo tikniyoolajiyadda tallaalku ay ka duwan tahay tan Pfizer iyo Moderna, haddana ma aha fikrad cusub. Tallaalka COVID iyo AstraZeneca ee COVID - oo loo oggolaaday in loo adeegsado Midowga Yurub iyo Boqortooyada Ingiriiska bishii Janaayo (FDA waxay hadda sugaysaa xog laga helay tijaabada caafimaad ee AstraZeneca ka hor inta aysan tixgelin oggolaanshaha Mareykanka, New York Times Warbixinnada) - waxay isticmaashaa tignoolajiyada adenovirus ee la midka ah. Johnson & Johnson waxay sidoo kale adeegsadeen tignoolajiyada si ay u abuuraan tallaalkooda Ebola, kaas oo la muujiyey inuu labadaba badbaado iyo waxtar u leeyahay soo saarista jawaabcelinta difaaca jirka.

Sidee ayuu waxtar u leeyahay tallaalka Johnson & Johnson COVID-19?

Tijaabo caafimaad oo ballaaran oo ku dhawaad ​​44,000 oo qof ah, tallaalka COVID-19 ee Johnson & Johnson ayaa lagu muujiyey inuu boqolkiiba 66 waxtar u leeyahay guud ahaan ka hortagga dhexdhexaad (oo lagu qeexay inuu leeyahay hal ama in ka badan astaamaha COVID-19) illaa COVID-19 daran (oo lagu garto gelitaanka ICU, neef-mareenka, ama xubnaha oo hawl-gab ah, iyo arrimo kale) 28 maalmood ka dib tallaalka, sida lagu sheegay war-saxaafadeed ka soo baxay shirkadda. (Xogta “waxaa loo gudbin doonaa joornaal dib loo eegay usbuucyada soo socda,” ayaa lagu yiri warsaxaafadeedka.)

Johnson & Johnson waxay sidoo kale wadaageen in heerka tallaalkiisa ee ka -hortagga COVID -ga dhexdhexaad ah ilaa daran uu ahaa 72 boqolkiiba Mareykanka, 66 boqolkiiba Latin America, iyo 57 boqolkiiba Koonfur Afrika (taas oo, marka la isku celceliyo, ay ku siineyso guud ahaan 66 boqolkiiba heerka waxtarka) . Haddii tirooyinkaasi ay u muuqdaan kuwo xoogaa hoos u dhacaya, waxaa xusid mudan in, marka la isbarbar dhigo, tallaalka hargabku uu yahay kaliya 40 ilaa 60 boqolkiiba waxtar u leh ka ilaalinta jirka hargabka, haddana weli wuxuu kaalin weyn ka qaataa dhimista isbitaallada iyo dhimashada la xiriirta hargabka. Dr. Olulade. (Waxa la xidhiidha: Tallaalka hargabku ma kaa ilaalin karaa Coronavirus?)

Xanuunka COVID-19 ee daran iyo Xogta Dhimashada

Marka ugu horeysa, heerka waxtarka tallaalka Johnson & Johnson ee 66 boqolkiiba ayaa laga yaabaa inuu u muuqdo mid aad u hooseeya, gaar ahaan markaad isbarbar dhigto heerka waxtarka Moderna (94.5 boqolkiiba wax ku ool ah) iyo Pfizer (“in ka badan boqolkiiba 90 wax ku ool ah,” sida laga soo xigtay shirkadda). Laakiin haddii aad si qoto dheer u qoddo, xogta Johnson & Johnson samee muuji natiijooyin rajo leh, gaar ahaan marka ay timaado kiisaska ugu daran ee COVID-19.

Dhammaan gobollada, tallaalku wuxuu ahaa 85 boqolkiiba waxtar leh si looga hortago COVID-19 daran, sida lagu sheegay warsaxaafadeedka Johnson & Johnson. Dhab ahaantii, shirkaddu waxay xustay in tallaalkeedu uu muujiyay "ka-hortag dhammaystiran oo ka dhan ah cusbitaalka la xiriira COVID iyo dhimashada" 28 maalmood ka dib tallaalka, "iyada oo aan la soo sheegin kiisas" isbitaal la xiriira COVID ama dhimasho ka mid ah kuwa helay tallaalka Johnson & Johnson.

Marka laga hadlayo waxyeellooyinka, Johnson & Johnson waxay sheegeen in tallaalkeeda COVID “guud ahaan si wanaagsan loo dulqaatay” dhammaan ka qaybgalayaasha tijaabada. Xogtii hore ee shirkaddu waxay soo jeedinaysaa in tallaalku sababi karo “waxyeellooyin fudud oo dhexdhexaad ah oo caadi ahaan la xiriira tallaalada,” oo ay ku jiraan daal, madax-xanuun, muruq xanuun, iyo xanuun goobta duritaanka.

Noocyada COVID-19

Si ka duwan daraasadaha Pfizer iyo Moderna, tijaabada tallaalka Johnson & Johnson waxaa ku jira natiijooyin gobollo badan - oo ay ku jiraan kuwa dhowaan lagu arkay kor u kac kiisaska COVID oo ay sababeen noocyo kala duwan oo fayraska ah. "[Noocyadan] waxaa laga yaabaa inaysan ahayn kuwa awood badan markii tallaaladii hore la darsay," ayuu yiri Dr. Olulade. Dabcan, cilmi-baarayaashu hadda waxay eegayaan sida waxtarka leh dhammaan Tallaallada COVID-19 waxaa laga yaabaa inay jirka ka ilaaliyaan noocyada kala duwan ee COVID-19. Hadda, Dr. Busse wuxuu leeyahay kala duwanaanshaha UK "aanay u badnayn inuu welwel ka qabo tallaallada COVID." Si kastaba ha ahaatee, waxay ku dartay, halkaas waa wararka la isla dhexmarayo ee ah in noocyada COVID ee ka imanaya Koonfur Afrika iyo Brazil ay “beddeli karaan habka unugyada difaaca jirka ay ula falgalaan fayraska” oo ay suuragal tahay inay ka dhigaan difaacayaasha difaaca “kuwo aan waxtar lahayn.” (Laxiriira: Waa maxay Sababaha cusub ee COVID-19 ay si dhakhso leh ugu faafayaan?)

Taasi waxay tidhi, iyadoo laga yaabo in tallaalku aanu ka hortagin caabuqa COVID-19, waxay u muuqataa inay dadka ka caawinayso inay ka fogaadaan waxa ugu xun ee fayraska. "Taasi waxay sidoo kale la macno tahay inay awood u leedahay inay yareyso culeyska saaran nidaamkayaga daryeelka caafimaad ee culeyska badan leh oo nagu soo dhoweynaya iftiinkaas dhammaadka tunnel-ka," ayuu yiri Dr. Olulade.

"Waxa kale oo muhiim ah in la xusuusto in sida ugu dhakhsaha badan aan u tallaali karno dadka, isbeddellada yar ee fayrasku waa inay is -beddelaan oo ay ku soo celiyaan," ayuu raaciyay Dr. Olulade. "Taasi waa sababta aan ugu baahan nahay inaan qof walba [tallaalno] sida ugu dhaqsaha badan."

Immisa qiyaasood oo ah tallaalka Johnson & Johnson COVID-19 ayaad u baahan tahay?

Marka laga reebo waxtarka tallaalka laftiisa, khubaradu waxay yiraahdeen tallaalka Johnson & Johnson's COVID ayaa sidoo kale rajo leh maxaa yeelay waxay u baahan tahay hal tallaal oo keliya, halka tallaallada Pfizer's iyo Moderna mid kastaa uu u baahan yahay laba tallaal oo loo kala saaro dhowr toddobaad.

"Tani dhab ahaantii waxay noqon kartaa mid wax ka beddeleysa ciyaarta," ayuu yiri Dr. Olulade. "Waxaan aragnaa in bukaannada qaarkood, nasiib darro, aysan dib ugu soo laaban qiyaastoodii labaad," marka habkan hal-iyo-lagu sameeyay wuxuu u tarjumi karaa tallaallo badan guud ahaan.

Faa'iido kale oo weyn u leh tallaalka COVID-19 ee Johnson & Johnson? Qiyaasaha ayaa sida muuqata si sahlan loo kaydiyo loona qaybiyo marka loo eego tallaalada Pfizer iyo Moderna, iyadoo ay ugu mahadcelinayaan adeegsiga tikniyoolajiyadda tallaalka adenovector. “Adenovirus [tallaalka Johnson & Johnson] waa ka raqiisan yahay mana aha mid jilicsan [sida mRNA ee tallaallada Pfizer iyo Moderna],” kan dambe oo u baahan kaydinta heerkul aad u qabow, ayuu sharraxay Dr. Busse. "Tallaalka Johnson & Johnson wuxuu deggan yahay qaboojiyaha ilaa saddex bilood, taas oo sahlaysa in markab la qaybiyo oo loo qaybiyo kuwa u baahan."

Sidee buu tallaalka Johnson & Johnson u saameeya gudbinta COVID-19?

"Waa goor hore in la sheego," ayuu yiri Prabhjot Singh, MD, Ph.D., lataliyaha caafimaadka iyo sayniska ee CV19 CheckUp, qalab online ah oo kaa caawinaya qiimeynta halista COVID-19. Taasi waxay u socotaa dhammaan tallaalada COVID-19 ee aan aragnay ilaa hadda BTW, ma aha Johnson & Johnson oo kaliya, ayuu qoray Dr. Singh. "Daraasadaha hore waxay soo jeedinayaan in khatarta gudbinta ay hoos u dhacdo ka dib marka la tallaalo, laakiin jawaabta saxda ah waxay u baahan tahay daraasad rasmi ah," ayuu sharaxay.

Mar haddii aan weli la garanayn saamaynta tallaallada ee gudbinta COVID, waxaa aad uga sii muhiimsan inaad sii waddo xidhashada waji-xidhka oo aad ka fogaato dadka ka baxsan gurigaaga, ayuu yidhi Dr. Olulade. (Sug, ma tahay inaad laba-duubto si aad isaga ilaaliso COVID-19?)

Khadka hoose: Dhammaan tallaaladan waxay u muuqdaan inay bixiyaan difaac weyn oo ka dhan ah COVID-19, oo aad u fiican. Sidaas oo ay tahay, “tallaalku ma aha ruqsad lagu dejiyo ilaaliyahaaga,” ayuu yiri Dr. Olulade. "Waa inaan si naf -hurnimo ah uga fikirnaa caafimaadka iyo samaqabka dadka kale ee aan weli la tallaalin oo aan weli ka ilaalin COVID."

Xogta ku jirta sheekadani waa mid sax ah ilaa wakhtiga la daabacay. Iyada oo cusboonaysiinta ku saabsan coronavirus COVID-19 ay sii socoto, waxaa suurtogal ah in qaar ka mid ah macluumaadka iyo talooyinka sheekadan la beddelo tan iyo markii la daabacay bilowgii. Waxaan kugu dhiirigelinaynaa inaad si joogto ah ula xiriirto ilaha sida CDC, WHO, iyo waaxda caafimaadka dadweynaha ee deegaankaaga si aad u hesho xogta ugu dambaysa iyo talooyinka.

Dib u eegis loogu talagalay