Tijaabooyinka Farmashiyaha

Qanacsan

• Waa maxay baaritaanka dawooyinka?
• Maxaa loo adeegsadaa?
• Maxaan ugu baahanahay baaritaanka daawada daawada?
• Maxaa dhacaya inta lagu jiro baaritaanka daawada?
• Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
• Ma jiraan wax khatar ah oo imtaxaanku leeyahay?
• Maxay natiijooyinka ka dhigan yihiin?
• Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka dawooyinka dawooyinka?
• Tixraacyo

Waa maxay baaritaanka dawooyinka?

Farmashiye-dhaqameedka, oo sidoo kale loo yaqaan 'pharmacogenomics', waa daraasad ku saabsan sida hiddo-wadayaashu u saameeyaan jawaabta jirka ee daawooyinka qaarkood. Hiddo-wadayaashu waa qaybo ka mid ah hidde-sideyaasha DNA ee laga soo gudbiyay hooyadaa iyo aabbahaa Waxay sitaan macluumaad go'aamiya astaamahaaga gaarka ah, sida dhererka iyo midabka indhaha. Hidda-wadahaagu sidoo kale wuxuu saameyn ku yeelan karaa sida ay ammaan iyo waxtar ugu yeelan karto daroogo gaar ah adiga.

Hidda-wadaha ayaa sababi kara in isla daawo isku qiyaas ah ay dadka u saameyso siyaabo aad u kala duwan. Hiddo-wadaha ayaa sidoo kale laga yaabaa inay sabab u tahay in dadka qaarkood ay saameyn xun ku yeeshaan daawada, halka kuwa kalena aysan lahayn.

Tijaabinta dawada dawada waxay fiirisaa hiddo-wadayaasha qaaska ah si ay kaaga caawiso soo saarista noocyada daawooyinka iyo qiyaasaha kugu habboon adiga.

Magacyada kale: dawada dawooyinka, baaritaanka dawooyinka

Maxaa loo adeegsadaa?

Tijaabada dawada dawada waxaa loo isticmaali karaa:

• Soo ogow in daawo cayiman wax kuu tareyso
• Raadi waxa ugu fiican ee qiyaasta ay adiga kuu noqon karto
• Saadaal inaad saameyn caafimaad oo daran ku yeelan doonto daawo

Maxaan ugu baahanahay baaritaanka daawada daawada?

Bixiyaha xanaanada caafimaadkaaga ayaa laga yaabaa inuu dalbado baaritaanadan kahor intaadan bilaabin daawo cayiman, ama hadaad qaadaneyso daawo aan shaqeynaynin iyo / ama keenaysa waxyeelo xun.

Tijaabooyinka Farmashiyadeed ayaa kaliya loo heli karaa tiro kooban oo daawooyin ah. Hoos waxaa ku yaal qaar ka mid ah daawooyinka iyo hiddo-wadayaasha la tijaabin karo. (Magacyada hiddo-wadaha waxaa badanaa lagu bixiyaa xarfo iyo lambarro.)

Maxaa dhacaya inta lagu jiro baaritaanka daawada?

Baaritaanka badanaa waxaa lagu sameeyaa dhiig ama candhuuf.

Tijaabada dhiigga, xirfadle daryeel caafimaad ayaa tijaabo dhiig ah ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.

Tijaabada candhuufta, Weydii bixiyaha xanaanada caafimaadkaaga tilmaamo ku saabsan sida loo bixiyo tijaabadaada.

Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?

Badanaa uma baahnid wax diyaargarow gaar ah oo loogu talagalay baaritaanka dhiigga. Haddii lagaa qaadayo baaritaanka candhuufta, waa inaanad wax cunin, wax cabbin, ama sigaar cabbin 30 daqiiqo baaritaanka ka hor.

Ma jiraan wax khatar ah oo imtaxaanku leeyahay?

Khatar aad u yar baa jirta in dhiig lagaa qaado. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan.

Khatar malahan in baaritaanka candhuufta lagaa qaado.

Maxay natiijooyinka ka dhigan yihiin?

Haddii lagaa baaray ka hor intaadan bilaabin daaweynta, baaritaanka wuxuu muujin karaa in daawo ay u badan tahay inay waxtar yeelanayso iyo / ama haddii aad halis ugu jirto waxyeelo daran. Tijaabooyinka qaarkood, sida kuwa loogu tala galay dawooyinka qaarkood ee daweeya suuxdinta iyo HIV, waxay muujin karaan inaad qatar ugu jirto waxyeelo nafta halis galisa. Hadday sidaas tahay, adeeg bixiyahaagu wuxuu isku dayi doonaa inuu helo daaweyn kale.

Tijaabooyinka dhaca ka hor iyo inta aad ku jirtid daaweynta ayaa ka caawin kara bixiyahaaga daryeelka caafimaadka inuu ogaado qiyaasta saxda ah.

Haddii aad su'aalo ka qabtid natiijooyinkaaga, la hadal daryeel caafimaad bixiyahaaga.

Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.

Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka dawooyinka dawooyinka?

Baaritaanka dawooyinka waxaa kaliya loo isticmaalaa si loo ogaado jawaabta qofka ee daawo gaar ah. Maaha wax la mid ah baaritaanka hidda-socodka. Badi tijaabooyinka hiddo-wadaha waxaa loo isticmaalaa in lagu caawiyo baaritaanka cudurrada ama halista cudurka ka imaan karta, in la aqoonsado xiriirka qoyska, ama lagu aqoonsado qof baaritaanka dambiyeed.

Tixraacyo

1. Hefti E, Blanco J. Diiwaangelinta Tijaabinta Pharmacogenomic ee Nidaamyada Adeegsiga Erey-bixinta ee hadda (CPT) Xeerarka, Dib-u-eegista Ku-Dhaqanka Hore iyo Kuwa Hadda J AHIMA [Internet]. 2016 Jan [tixraacay 2018 Jun 1]; 87 (1): 56–9. Waxaa laga heli karaa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
2. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington DC: Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2018. Tijaabooyinka Farmashiyaha; [cusboonaysiiyay 2018 Jun 1; daliishaday 2018 Jun 1]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/pharmacogenetic-tests
3. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington DC: Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2018. Caalamka ee Tijaabada hidaha; [cusboonaysiiyay 2017 Nofeembar 6; daliishaday 2018 Jun 1]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/articles/genetic-testing?start=4
4. Mayo Clinic: Xarunta Daaweynta Gaarka ah [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. Tijaabinta hiddo-wadaha; [daliishaday 2018 Jun 1]; [ilaa 3 shaashad]. Waxaa laga heli karaa: http://mayoresearch.mayo.edu/center-for-individualized-medicine/drug-gene-testing.asp
5. Mayo Clinic: Xarunta Daaweynta Gaarka ah [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. CYP2D6 / Tamoxifen Pharmacogenomic Lab Imtixaan; [daliishaday 2018 Jun 1]; [ilaa 5 shaashad].Waxaa laga heli karaa: http://mayoresearch.mayo.edu/center-for-individualized-medicine/cyp2d6-tamoxifen.asp
6. Mayo Clinic: Xarunta Daaweynta Gaarka ah [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. HLA-B * 1502 / Carbamazepine Farmashiyo-baarista Shaybaarka; [daliishaday 2018 Jun 1]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab1502-carbamazephine.asp
7. Mayo Clinic: Xarunta Daaweynta Gaarka ah [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. HLA-B * 5701 / Abacavir Pharmacogenomic Lab Lab; [daliishaday 2018 Jun 1]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab5701-abacavir.asp
8. Mayo Clinic: Mayo Laboratories [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1995–2018. Aqoonsiga Tijaabada: PGXFP: Guddi Farmashiyeed Farmashiyoolaji: Tijaabooyin; [daliishaday 2018 Jun 1]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
9. Machadka Kansarka Qaranka [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Qaamuuska NCI ee Shuruudaha Kansarka: hiddo-wadaha; [daliishaday 2018 Jun 1]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q;=gene
10. Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Tijaabooyinka Dhiigga; [daliishaday 2018 Jun 1]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/blood-tests
11. NIH Machadka Qaranka ee Sayniska Caafimaadka Guud [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Farmashiyaha; [cusbooneysiiyay 2017 Oct; daliishaday 2018 Jun 1]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
12. NIH Maktabadda Qaranka ee Caafimaadka: Tixraaca Hoyga Guryaha [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Waa maxay daawada dawooyinka ?; 2018 Meey 29 [daliishaday 2018 Jun 1]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
13. Caafimaadka UF: Jaamacadda Florida Health [Internet]. Jaamacadda Florida; c2018. Sidee hiddo-wadahaagu u saameynayaa daawooyinka adiga kugu habboon; 2016 Jan 11 [cusbooneysiiyay 2018 Jun 1; daliishaday 2018 Jun 1]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are-right-you
14. UW Health American Hospital Carruurta [Internet]. Madison (WI): Jaamacadda Wisconsin Isbitaalada iyo Maamulka Rugta; c2018. Caafimaadka Carruurta: Farmashiyeyaasha; [daliishaday 2018 Jun 1]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.uwhealthkids.org/kidshealth/en/parents/pharmacogenomics.html/

Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.