Cudurka 'Cryptococcosis'

Cudurka loo yaqaan 'Cryptococcosis' waa infekshan ku dhaca fangaska Cilmiga 'Cryptococcus neoformans' iyo Cryptococcus gattii.

C neoformans iyo C gattii waa fangaska keena cudurkan. Infekshinka leh C neoformans adduunka oo dhan ayaa laga arkaa. Infekshinka leh C gattii waxaa badanaa lagu arkay gobolka Pacific Northwest ee Mareykanka, British Columbia ee Kanada, Koonfur-bari Aasiya, iyo Australia. Cryptococcus waa fangaska ugu caansan ee sababa infekshinka halista ah ee adduunka oo dhan.

Labada nooc ee fungi waxaa laga helaa carrada. Haddii aad ku neefsatid fangaska, wuxuu ku dhacaa sambabadaada. Infekshanku wuu iska bixi karaa kaligiis, wuxuu ku sii jiri karaa sambabada oo keliya, ama wuxuu ku faafi karaa jirka oo dhan (faafiyaa). C neoformans infekshinka waxaa badanaa lagu arkaa dadka leh habka difaaca jirka oo daciif ah, sida kuwa:

• Aad qabtid HIV / AIDS
• Qaado qadar sare oo ah daawooyinka corticosteroid
• Kansarka
• Waxay ku jiraan dawooyinka kemotherabi ee kansarka
• Aad qabto cudurka Hodgkin
• Ma lagugu tallaalay xubin

C gattii waxay saameyn ku yeelan kartaa dadka leh nidaamka difaaca jirka ee caadiga ah.

C neoformans ayaa ah waxa ugu badan ee nolosha halista u ah infekshanka fungal ee dadka qaba HIV / AIDS.

Dadka da'doodu u dhaxayso 20 ilaa 40 sano jir ayaa qaba infekshankan.

Infekshanku wuxuu ku faafi karaa maskaxda dadka qaba daciifnimada habka difaaca jirka. Calaamadaha neerfaha (maskaxda) si tartiib tartiib ah ayey u bilowdaan. Dadka badankood waxay leeyihiin barar iyo cuncun maskaxda iyo lafdhabarta marka la ogaado. Calaamadaha infekshanka maskaxda waxaa ka mid noqon kara:

• Qandho iyo madax xanuun
• Qallooca qoorta
• Lalabbo iyo matag
• Aragga oo xumaada ama aragti laba-laaban
• Jahwareer

Infekshanku wuxuu sidoo kale saameyn ku yeelan karaa sambabaha iyo xubnaha kale. Calaamadaha sambabaha waxaa ka mid noqon kara:

• Neefsashada oo ku adkaata
• Qufac
• Laab xanuun

Calaamadaha kale waxaa ka mid noqon kara:

• Lafa xanuun ama danqasho lafaha naaska
• Daal
• Finan maqaarka ah, oo ay ku jiraan dhibco casaan ah (petechiae), boogaha, ama nabarrada kale ee maqaarka
• Dhidid - wax aan caadi ahayn, siyaado ah habeenkii
• Qanjirrada oo barara
• Miisaan lumis aan ula kac ahayn

Dadka leh nidaam caafimaad oo caafimaad waxay yeelan karaan astaamo haba yaraatee.

Bixiyaha xanaanada caafimaadka ayaa sameyn doona baaritaan jireed wuxuuna weydiin doonaa astaamaha iyo taariikhda safarka. Imtixaanka jireed ayaa laga yaabaa inuu muujiyo:

• Neefta oo aan caadi ahayn
• Qiyaasta garaaca wadnaha
• Qandho
• Isbedelada xaalada maskaxda
• Qoorta adag

Tijaabooyinka la qaadi karo waxaa ka mid ah:

• Dhaqanka dhiiga si loo kala saaro labada fungi
• Baadhitaanka CT ee madaxa
• Dhaqanka xaakada iyo wasakhda
• Cad ka-qaadista sambabka
• Bronchoscopy iyo bulchoalveolar wasaqda
• Tubada laf-dhabarka si loo helo saamiga dareeraha maskaxda (CSF)
• Dhaqanka Cerebrospinal fluid (CSF) iyo baaritaano kale si loo hubiyo astaamaha cudurka
• Raajo xabadka ah
• Tijaabinta 'Cryptococcal antigen' (waxay raadineysaa maaddooyin gaar ah oo laga soo daadinayo gidaarka unugga Cryptococcus fangas ku shub dhiigga ama CSF)

Daawooyinka fungal waxaa loo qoraa dadka qaba cudurka loo yaqaan 'cryptococcus'.

Daawooyinka waxaa ka mid ah:

• Amphotericin B (wuxuu yeelan karaa waxyeelo daran)
• Flucytosine
• Fluconazole

Ka-qaybgalka nidaamka neerfaha ee bartamaha badanaa wuxuu keenaa dhimasho ama wuxuu u horseedaa dhaawac joogto ah.

Wac adeeg bixiyahaaga haddii aad isku aragto calaamadaha cudurka loo yaqaan 'cryptococcosis', gaar ahaan haddii aad daciifto habka difaaca jirka.

C. neoformans var. cudurka neoformans; C. neoformans var. infekshinka gatti; C. neoformans var. infekshinka grubii

• Cryptococcus - cutaneous on gacanta
• Cryptococcosis wejiga
• Fungus

Kauffman CA, Chen SC-A. Cudurka 'Cryptococcosis'. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 317.

JR oo qumman Cudurka 'Cryptococcosis'Cryptococcus neoformans iyo Cryptococcus gattii). Gudaha: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, iyo Bennett Mabaadi'da iyo Ku Dhaqanka Cudurada faafa. 9aad. Philadelphia, PA: Elsevier; 2020: cutubka 262.

Robles WS, Ameen M. Cryptococcosis. Gudaha: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson IH, eds. Daaweynta Cudurka Maqaarka: Istaraatijiyadaha Daaweynta Oo dhameystiran. 5aad. Philadelphia, PA: Elsevier; 2018: cutubka 49.