Niacinamide

Qanacsan

• Waxtar u leh ...
• Suurtagal inay wax ku ool u tahay ...
• Suurtagal ma ahan waxtar ...
• Cadeymo aan ku filneyn in lagu qiimeeyo wax ku oolnimada ...
• Taxaddarrada gaarka ah & digniinta:

Waxaa jira laba nooc oo fiitamiin B3 ah. Hal nooc waa niacin, kan kalena waa niacinamide. Niacinamide waxaa laga helaa cuntooyin badan oo ay ku jiraan khamiir, hilib, kalluun, caano, ukumo, khudaar cagaaran, digir, iyo badarka. Niacinamide sidoo kale waxaa laga helaa fiitamiin B badan oo isku dhafan oo leh fiitamiinno kale oo B ah. Niacinamide sidoo kale waxaa lagu abuuri karaa jirka laga bilaabo niacin.

Ha ku qaldin niacinamide iyo niacin, NADH, nicotinamide riboside, inositol nicotinate, ama tryptophan. Eeg liisaska kaladuwan ee mawduucyadan.

Niacinamide ayaa afka looga qaataa si looga hortago yaraanshaha fitamiin B3 iyo xaaladaha la xariira sida pellagra. Waxaa sidoo kale afka looga qaadaa finanka, sonkorowga, kansarka afka, lafo xanuunka, iyo xaalado kale oo badan. Si kastaba ha noqotee, ma jirto caddayn cilmi ah oo wanaagsan oo lagu taageerayo adeegsigaas.

Niacinamide sidoo kale waxaa loo mariyaa maqaarka finanka, cambaarta, iyo xaaladaha kale ee maqaarka. Sidoo kale ma jirto caddayn wanaagsan oo lagu taageerayo adeegsigaas.

Daawooyinka Dabiiciga ah ee Xogta Dhamaystiran waxay qiimeysaa waxtarka ku saleysan caddeynta sayniska iyadoo loo eegayo cabirka soo socda: Wax ku ool ah, Suurta gal ah inuu wax ku ool yahay, suurtagal tahay wax ku ool ah, macquul ahaan waxtar la'aan, suurtagal ahaan waxtar la'aan, waxtar la'aan, iyo caddayn ku filan oo lagu qiimeeyo.

Qiimeynta waxtarka ee NIACINAMIDE waa sida soo socota:

Waxtar u leh ...

• Cudur uu sababo niacin yaraanta (pellagra). Niacinamide waxaa ansixiyay Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA) adeegsigaas. Niacinamide ayaa mararka qaar laga doorbidaa niacin maxaa yeelay ma keento "flushing," (guduudasho, cuncun iyo xoqid), saameyn dhinaca daaweynta ah niacin.

Suurtagal inay wax ku ool u tahay ...

• Finanka. Cilmi baaris hore waxay muujineysaa in qaadashada kaniiniyada ay ku jiraan niacinamide iyo waxyaabo kale 8 todobaad ay wanaajineyso muuqaalka maqaarka ee dadka qaba finanka. Cilmi baaris kale waxay muujineysaa in la mariyo kareem ay ku jirto niacinamide ay wanaajineyso muuqaalka maqaarka dadka qaba finanka.
• Sonkorowga. Daraasadaha qaarkood waxay muujinayaan in qaadashada niacinamide ay ka caawin karto kahortagga luminta soosaarka insulin ee carruurta iyo dadka waaweyn ee halista ugu jira nooca 1aad ee sonkorowga. Waxa kale oo laga yaabaa inay ka hortagto luminta soosaarka insulin waxayna yareysaa qiyaasta insulin-ta ay u baahan yihiin carruurta dhawaan laga helay nooca 1aad ee sonkorowga. Si kastaba ha noqotee, niacinamide uma muuqato inay ka hortageyso horumarinta nooca 1 ee sonkorowga carruurta halista ku jirta. Dadka qaba sonkorowga nooca 2, niacinamide waxay umuuqataa inay gacan ka geysato ilaalinta wax soo saarka insulin-ka iyo hagaajinta xakamaynta sonkorta dhiigga.
• Heerarka sare ee fosfateetka dhiiga ku jira (hyperphosphatemia). Heerarka dhiigga sare ee fosfooraska waxaa sababi kara shaqada kelyaha oo yaraata. Dadka qaba kelyaha oo hawlgab ah oo ku jira hemodialysis-ka oo leh heerar sare oo fosfoosto dhiig ah, qaadashada niacinamide waxay umuuqataa inay gacan ka geysaneyso yareynta heerarka fosfateerka markii lala qaato ama aan lahayn xirmooyinka fosfateerka.
• Kansarka madaxa iyo qoorta. Cilmi baaris ayaa muujisay in qaadashada niacinamide inta la qaadanaayo radiotherapy iyo nooc daaweyn ah oo loo yaqaan karboonka ay ka caawin karto xakamaynta koritaanka burooyinka iyo kordhinta badbaadada dadka qaar ee qaba kansarka cunaha. Qaadashada niacinamide inta aad qaadanaysid shucaaca iyo karboonka waxay u muuqataa inay ka faa'iideysaneyso dadka qaba kansarka ku dhaca dhuunta oo iyaguna dhiigyacab ah. Waxay sidoo kale umuuqataa inay caawineyso dadka qaba burooyinka ay ka go'antahay ogsijiinta.
• Kansarka maqaarka. Qaadashada niacinamide waxay umuuqataa inay kaa caawinayso kahortaga kansarka maqaarka cusub ama dhibco hore (actinic keratosis) inay ku samaysmaan dad leh taariikh kansarka maqaarka ama actinic keratosis.
• Cudurka Osteoarthritis. Qaadashada niacinamide waxay umuuqataa inay hagaajineyso dabacsanaanta wadajirka iyo yareynta xanuunka iyo bararka dadka qaba cudurka osteoarthritis. Sidoo kale, dadka qaarkiis ee qaba cudurka osteoarthritis ee qaata niacinamide ayaa laga yaabaa inay u baahdaan inay yareeyaan daawooyinka xanuunka.

Suurtagal ma ahan waxtar ...

• Burada maskaxda. Daraasad hore waxay muujineysaa in daaweynta dadka qaba qalliinka lagaa saaray burooyinka maskaxda ee niacinamide, radiotherapy, iyo karbogen aysan wanaajinaynin badbaadada marka loo eego shucaaca ama shucaaca iyo karboonka.
• Kansarka kaadiheysta. Ku daaweynta dadka qaba kansarka kaadi heysta niacinamide, radiotherapy, iyo karbogen ma muuqato inay yareyneyso koritaanka burooyinka ama waxay wanaajineysaa badbaadada marka la barbar dhigo shucaaca ama shucaaca iyo karboonka.

Cadeymo aan ku filneyn in lagu qiimeeyo wax ku oolnimada ...

• Cudur indhaha ku dhaca oo u horseeda aragga luminta dadka waaweyn (da 'ku dhaca da'da oo ku dhaca da'da ama AMD). Cilmibaaris hore waxay soo jeedineysaa in qaadashada niacinamide, fitamiin E, iyo lutein muddo hal sano ah ay wanaajineyso sida wanaagsan ee xubinta taranka ay ugu shaqeyso dadka qaba aragga la xiriira da'da oo ay ugu wacan tahay dhaawaca soo gaadhay isha.
• Maqaarka gaboobay. Daraasad hore waxay muujisay in kareemka ay kujirto 5% niacinamide wajiga ay wanaajineyso ubaxnimada, duuduubnaanta, dabacsanaanta, iyo guduudashada haweenka maqaarka gaboobaya sababo la xiriira qorraxda.
• Cambaarta (atopic dermatitis). Cilmibaaris hore waxay muujisay in kareemka la mariyo oo ay kujirto 2% niacinamide ay yareyso luminta biyaha waxayna hagaajisaa fuuqbaxa, waxayna yareysaa casaanka iyo miisaanka, dadka qaba cambaarta
• Feejignaanta maqnaanshaha-jahwareerka (ADHD). Waxaa jira cadeymo iska soo horjeeda oo ku saabsan waxtarka niacinamide oo lagu daro fitamiino kale oo loogu talagalay daaweynta ADHD.
• Guduudasho maqaarka oo ay sababtay dhaawac ama cuncun (erythema). Daraasad hore waxay muujisay in la mariyo kareem ay ku jirto niacinamide ay yareyneyso maqaarka maqaarkiisa, qalalan, iyo cuncun ay keeneen dawada finanka isotretinoin.
• Cudurka kelyaha ee muddada dheer (cudur kelyaha ah oo joogto ah ama CKD). Cilmibaaris hore waxay muujisay qaadashada niacinamide inaysan gacan ka geysanayn yareynta cuncunka dadka qaba cudurka kalyaha.
• Maqaarka maqaarka oo mugdi ah (melasma). Cilmibaaristii ugu horreysay waxay muujineysaa in codsashada huurka oo ay ku jiraan 5% niacinamide ama 2% niacinamide oo leh 2% tranexamic acid muddo 4-8 toddobaad ah ay ka caawineyso yareynta maqaarka dadka leh maqaarka madow.
• Kansarka ka bilaabma unugyada dhiiga cad (non-Hodgkin lymphoma). Cilmibaarista hore waxay muujineysaa in qaadashada niacinamide oo qeyb ka ah daaweynta daroogada loo yaqaan 'vorinostat' laga yaabo inay ka caawiso dadka qaba lymphoma inay galaan cafiska.
• Xaalad maqaar oo ku keenta wejiga casaan (rosacea). Cilmi baaris hore waxay muujineysaa in qaadashada kaniiniyada ay ku jiraan niacinamide iyo waxyaabo kale 8 todobaad ay wanaajineyso muuqaalka maqaarka dadka qaba rosacea.
• Maqaas qallafsan, maqaarka oo maqaarka ku yaal madaxa iyo wejiga (seborrheic dermatitis). Daraasad hore waxay muujisay in la mariyo kareem ka kooban 4% niacinamide ay yareyn karto guduudashada iyo maqaarka maqaarka dadka qaba cudurka loo yaqaan 'seborrheic dermatitis'.
• Khamriga.
• Cudurka Alzheimer.
• Arthritis.
• Hoos u dhaca xusuusta iyo xirfadaha fekerka ee sida caadiga ku dhaca da'da.
• Niyad jab.
• Dhiig kar.
• Cudurka dhaqdhaqaaqa.
• Cudurka premenstrual syndrome (PMS).
• Xaaladaha kale.

Cadeymo dheeraad ah ayaa loo baahan yahay si loogu qiimeeyo niacinamide adeegsigaan.

Niacinamide waxaa laga samayn karaa niacin jirka ku jirta. Niacin waxaa loo beddelaa niacinamide markii lagu qaato qadar ka badan inta jidhku u baahan yahay. Niacinamide si fudud ayaa loogu dhex milmaa biyaha oo si fiican ayuu u nuugaa markii afka laga qaato.

Niacinamide ayaa looga baahan yahay shaqada saxda ah ee dufanka iyo sonkorta jirka ku jirta iyo ilaalinta unugyada caafimaadka qaba.

Si ka duwan niacin, niacinamide wax saameyn ah kuma lahan dufanka mana loo isticmaali karo in lagu daaweeyo kolestaroolka sare ama heerarka dufanka badan ee dhiigga ku jira. Markii afka lagaa qaado: Niacinamide waa KU SOO DHAWEYN SAFE dadka waaweyn badankood marka lagu qaato qaddarka lagu taliyay. Si ka duwan niacin, niacinamide ma keento dheecaan. Si kastaba ha noqotee, niacinamide waxay sababi kartaa waxyeelo yar sida calool xanuun, gaas, wareer, finan, cuncun, iyo dhibaatooyin kale. Si loo yareeyo halista waxyeellooyinkan, dadka waaweyni waa inay ka fogaadaan qaadashada niacinamide ee qaadasho ka badan 35 mg maalintii.

Marka qaadashada ka badan 3 garaam maalintii ee niacinamide la qaato, waxyeelo ka sii daran ayaa dhici karta. Kuwaas waxaa ka mid ah dhibaatooyinka beerka ama sonkorta dhiigga oo sareysa.

Marka la mariyo maqaarka: Niacinamide waa BADBAADO KU SAABSAN. Kareemka Niacinamide wuxuu sababi karaa gubasho yar, cuncun, ama casaan.

Taxaddarrada gaarka ah & digniinta:

Uurka iyo nuujinta: Niacinamide waa KU SOO DHAWEYN SAFE loogu talagalay haweenka uurka leh iyo kuwa naas nuujinaya marka lagu qaato qaddarka lagu taliyay. Qiyaasta ugu badan ee lagu taliyo ee niacin ee haweenka uurka leh ama naas nuujinaya waa 30 mg maalintii dumarka ka yar 18 sano, iyo 35 mg maalintii dumarka ka weyn 18 sano.

Caruurta: Niacinamide waa KU SOO DHAWEYN SAFE marka afka lagaga qaado qaddarka lagula taliyay da 'kasta oo da' ah. Laakiin carruurtu waa inay ka fogaadaan qaadashada qiyaasta niacinamide ee ka sarreysa xadka sare ee maalinlaha ah, kuwaas oo ah 10 mg oo loogu talagalay carruurta 1-3 sano jir ah, 15 mg loogu talagalay carruurta 4-8 sano jir ah, 20 mg loogu talagalay carruurta 9-13 sano jir ah, iyo 30 mg carruurta da'doodu tahay 14-18 sano.

Xasaasiyadda: Niacinamide waxay ka dhigi kartaa xasaasiyad aad u daran maxaa yeelay waxay keenaan histamine, kiimikada masuulka ka ah calaamadaha xasaasiyadda, in la sii daayo.

Sonkorowga: Niacinamide waxay kordhin kartaa sonkorta dhiiga. Dadka qaba sonkorowga ee qaata niacinamide waa inay si taxadar leh u hubiyaan sonkorta dhiigooda.

Xameetida: Niacinamide waxay sii xumayn kartaa cudurka xameetida.

Turqo: Xaddi badan oo niacinamide ah ayaa laga yaabaa inay keento gout.

Kelyaha sifeyntiisa: Qaadashada niacinamide waxay umuuqataa inay kordhinayso halista heerarka dhiig-karka dhiigga ee hooseeya ee dadka qaba kelyaha oo hawlgab ah kuwaasoo ku jira sifaynta kalyaha.

Cudurka beerka: Niacinamide waxay kordhin kartaa dhaawaca beerka. Ha u isticmaalin haddii aad qabto cudurka beerka.

Caloosha ama boogaha mindhicirka: Niacinamide waxaa laga yaabaa inay boogaha sii xumeeyaan. Ha u isticmaalin haddii aad nabarro leedahay.

Qalliinka: Niacinamide waxaa laga yaabaa inuu farageliyo xakameynta sonkorta dhiigga inta lagu jiro iyo qalliinka kadib. Jooji qaadashada niacinamide ugu yaraan 2 toddobaad kahor qalliinka jadwalka ah.

Dhexdhexaad

Ka taxaddar isku-dhafkan.

Carbamazepine (Tegretol)

Jidhku wuu jajabiyaa Carbamazepine (Tegretol). Waxaa jira xoogaa walaac ah in niacinamide ay yareyn karto sida dhaqsaha badan ee jirku u burburiyo carbamazepine (Tegretol). Laakiin ma jiro macluumaad ku filan oo lagu ogaan karo inay tani muhiim tahay.

Daawooyinka waxyeelo u geysan kara beerka (Hepatotoxic drugs)

Niacinamide waxay waxyeeleyn kartaa beerka, gaar ahaan marka loo isticmaalo qiyaaso badan. Qaadashada niacinamide oo ay weheliso daawo sidoo kale waxyeelayn karta beerka waxay kordhin kartaa halista waxyeellada beerka. Ha u qaadan niacinamide haddii aad qaadanaysid daawo waxyeelayn karta beerka.

Daawooyinka qaar ee waxyeeli kara beerka waxaa kamid ah acetaminophen (Tylenol iyo kuwa kale), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporan) erythromycin (Erythrocin, Ilosone, kuwa kale), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), iyo kuwa kale oo badan.

Daawooyinka yareeya xinjirowga dhiigga (Daawooyinka Anticoagulant / Antiplatelet)

Niacinamide waxay yareyn kartaa xinjirowga dhiigga. Qaadashada niacinamide iyo dawooyinka sidoo kale gaabiya xinjirowga ayaa kordhin kara fursadaha nabarrada iyo dhiig baxa.

Daawooyinka qaar ee gaabiya xinjirowga dhiigga waxaa kamid ah aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), iyo kuwa kale.

Primidone (Mysoline)

Primidone (Mysoline) jirku wuu jajabiyaa. Waxaa jira xoogaa walaac ah in niacinamide ay yareyn karto sida ugu dhakhsaha badan ee jirka u burburo primidone (Mysoline). Laakiin ma jiro macluumaad ku filan oo lagu ogaan karo inay tani muhiim tahay.

Dhir iyo waxyaabo dheeri ah oo waxyeelayn kara beerka

Niacinamide waxay sababi kartaa waxyeelo beerka ah, gaar ahaan marka loo isticmaalo qiyaaso badan. Qaadashada niacinamide oo ay weheliso geedo kale ama dheeri ah oo waxyeelayn kara beerka ayaa kordhin kara halistaan. Qaar ka mid ah badeecadahan waxaa ka mid ah daawada, caleen borage, chaparral, comfrey, dehydroepiandrosterone (DHEA), jeermiska, kava, saliida pennyroyal, khamiirka cas, iyo kuwa kale.

Dhirta iyo nafaqada oo yareyn kara xinjirowga dhiigga

Niacinamide waxay yareyn kartaa xinjirowga dhiigga. Isticmaalka niacinamide oo ay weheliyaan geedo kale iyo waxyaabo dheeri ah oo sidoo kale gaabiya xinjirowga dhiigga ayaa kordhin kara halista dhiig-baxa dadka qaarkood. Qaar ka mid ah geedaha kale ee noocan ah waxaa ka mid ah Angelica, clove, danshen, toon, sinjibiil, Panax ginseng, iyo kuwo kale.

Ma jiraan wax la yaqaan oo la falgala cunnooyinka.

Qiyaasaha soo socda ayaa lagu bartay cilmi baarista sayniska:

DADKA WAAWEYN

Afka:

• Guud: Qaar ka mid ah alaabada dheeraadka ah ee nafaqada leh ayaa laga yaabaa inaysan si gooni ah ugu qorin liistada niacinamide. Taabadalkeed, waxaa laga yaabaa in lagu qoro niacin. Niacin waxaa lagu cabiraa niacin u dhiganta (NE). Qiyaas dhan 1 mg oo ah niacinamide waxay la mid tahay 1 mg NE. Gunooyinka cuntada ee maalinlaha ah ee lagu taliyo (RDAs) ee niacinamide ee dadka waaweyn waa 16 mg NE ragga, 14 mg NE haweenka, 18 mg NE haweenka uurka leh, iyo 17 mg NE haweenka nuujinaya.
• Finanka: Kiniinno ay ku jiraan 750 mg oo niacinamide ah, 25 mg oo zinc ah, 1.5 mg oo naxaas ah, iyo 500 mcg oo folic acid ah (Nicomide) hal mar ama laba jeer maalintii ayaa la isticmaalay. Sidoo kale, 1-4 kiniin oo ay ku jiraan niacinamide, azelaic acid, zinc, vitamin B6, copper, iyo folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) ayaa maalin kasta la qaataa.
• Calaamadaha yaraanta fitamiin B3 sida pellagra: 300-500 mg maalintii niacinamide waxaa lagu bixiyaa qadaryo kala duwan.
• Sonkorowga: Niacinamide 1.2 garaam / m² (aagga dusha sare ee jirka) ama 25-50 mg / kg ayaa loo isticmaalaa maalin kasta si loo yareeyo horumarka nooca 1aad ee sonkorowga. Sidoo kale, 0.5 garaam oo niacinamide ah saddex jeer maalintii ayaa loo isticmaalaa in lagu yareeyo horumarka nooca 2aad ee sonkorowga.
• Heerarka sare ee fosfateetka dhiiga ku jira (hyperphosphatemia): Niacinamide laga bilaabo 500 mg ilaa 1.75 garaam maalin kasta qiyaaso loo qaybiyay waxaa loo isticmaalaa 8-12 toddobaad.
• Cudurka kansarka ee cunaha: 60 mg / kg ee niacinamide waxaa la siiyaa 1-1.5 saacadood ka hor inta aan la neefsan karboonka (2% kaarboon laba ogsaydhka iyo 98% oksijiin) kahor iyo inta lagu jiro shucaaca.
• Kansarka maqaarka ee aan ahayn melanoma: 500 mg oo niacinamide ah hal mar ama laba jeer maalintii 4-12 bilood.
• Daaweynta osteoarthritis: 3 garaam oo niacinamide ah maalintii qiyaaso loo qaybiyay 12 toddobaad.

MAQAARKA:

• Finanka: Jel ka kooban 4% niacinamide laba jeer maalintii.

CARRUURTA

• Guud: Gunnada cuntada ee maalinlaha ah ee lagu taliyo (RDAs) ee loogu talagalay niacinamide ee carruurta waa 2 mg oo loogu talagalay dhallaanka 0-6 bilood jira, 4 mg NE oo loogu talagalay dhallaanka 7-12 bilood jira, 6 mg NE loogu talagalay carruurta 1-3 sano jir ah, 8 mg NE oo loogu tala galay caruurta 4-8 sano jir ah, 12 mg NE oo loogu tala galay caruurta da'doodu tahay 9-13 sano, 16 mg NE oo loogu talagay ragga da'doodu tahay 14-18 sano, iyo 14 mg NE oo loogu tala galay dumarka da'doodu tahay 14-18 sano.
• Finanka: Carruurta ugu yaraan 12 sano jir ah, 1-4 kiniin oo ay ku jiraan niacinamide, azelaic acid, zinc, vitamin B6, copper, iyo folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) ayaa maalin kasta la qaataa.
• Wixii pellagra: 100-300 mg oo niacinamide ah ayaa la siiyaa maalin kasta qadaryo kala duwan.
• Nooca 1aad ee sonkorowga: 1.2 garaam / m² (aagga dusha sare ee jirka) ama 25-50 mg / kg ee niacinamide ayaa loo isticmaalaa maalin kasta si loo yareeyo horumarka ama looga hortago cudurka macaanka nooca 1aad.

3-Pyridine Carboxamide, 3-Pyridinecarboxamide, Amide de l'Acide Nicotinique, B Complex Vitamin, Complex de Vitamines B, Niacinamida, Nicamid, Nicosedine, Nicotinamide, Nicotinic Acid Amide, Nicotylamidum, Pyridine-3-carboxamide, Vitamin B3, Vitamina B , Vitamine B3.

Si aad wax badan uga ogaato sida maqaalkan loo qoray, fadlan eeg Daawooyinka Dabiiciga ah ee Xogta Dhamaystiran habka.

1. Zhang Y, Ma T, Zhang P. Waxtarka iyo badbaadada nicotinamide ee fosfooraska ee bukaan socodka hemodialysis: Dib u eegis nidaamsan iyo falanqayn meta. Daawada (Baltimore). 2018; 97: e12731. Eeg aragti
2. Cannizzaro MV, Dattola A, Garofalo V, Del Duca E, Bianchi L. Yaraynta waxyeelada maqaarka isotretinoin ee afka: waxtarka 8% omega-ceramides, sonkorta hydrophilic, 5% niacinamide cream cream ee bukaanka finanka. G Ital Dermatol Venereol. 2018; 153: 161-164. Eeg aragti
3. Xarunta Tababarka Caafimaadka ee NICE (UK). Hyperphosphataemia oo ku jirta Cudurka Kelyaha ee Daran: Maaraynta Hyperphosphataemia ee Bukaannada qaba Marxaladda 4 ama 5 Cudurka Kelyaha ee Muddada dheer. Machadka Qaranka ee Caafimaadka iyo Daryeelka Sare: Tilmaamaha Caafimaadka. Manchester: Machadka Qaranka ee Caafimaadka iyo Daryeelka Sare (UK); 2013 Mar.
4. Cheng SC, Young DO, Huang Y, Delmez JA, Coyne DW. Tijaabinta, laba-indhoole, tijaabinta xakamaynta xakamaynta ee niacinamide ee yareynta fosfooraska bukaanada hemodialysis. Clin J Am Soc Nephrol. 2008 Jul; 3: 1131-8. Eeg aragti
5. Hoskin PJ, Rojas AM, Bentzen SM, Saunders MI. Daaweynta shucaaca oo leh karbogen iyo nicotinamide oo isku mid ah kansarka kaadiheysta. J Clin Oncol. 2010 Nofeembar 20; 28: 4912-8. Eeg aragti
6. Surjana D, Halliday GM, Martin AJ, Moloney FJ, Damian DL. Cudurka 'nicotinamide' wuxuu yareeyaa keratoses-ka ficil ee wajiga II tijaabooyin la kala soocay oo laba-indho la 'ah. J Invest Dermatol. 2012 Mee; 132: 1497-500. Eeg aragti
7. Omidian M, Khazanee A, Yaghoobi R, Ghorbani AR, Pazyar N, Beladimousavi SS, Ghadimi M, Mohebbipour A, Feily A. Saamaynta daweynta ee nikotiinka afka ee diidmada uremic pruritus: daraasad la kala soocay, laba-indhoole ah. Saudi J Kilyaha Dis Transpl. 2013 Sep; 24: 995-9. Eeg aragti
8. Nijkamp MM, Span PN, Terhaard CH, Doornaert PA, Langendijk JA, van den Ende PL, de Jong M, van der Kogel AJ, Bussink J, Kaanders JH. Cudurka epidermal ee koritaanka cuncunka ee kansarka laryngeal wuxuu saadaaliyaa saameynta isbeddelka hypoxia iyada oo lagu daro ku daweynta shucaaca degdega ah ee tijaabada la xakameeyey. Kansarka Eur J 2013 Oktoobar; 49: 3202-9. Eeg aragti
9. Martin AJ, Chen A, Choy B, iyo al. Nicotinamide afka ah si loo yareeyo kansarka ficil ahaan: Wajiga 3 ee tijaabada kontoroolka laba-indhoolayaasha ah. J Clin Oncol 33, 2015 (alaab; abstr 9000).
10. Lee DH, Oh IY, Koo KT, Suk JM, Jung SW, Park JO, Kim BJ, Choi YM. Yaraynta fiiqitaanka wejiga ka dib daaweynta ee la isku daro niikadaamide la mariyo iyo tranexamic acid: a randomized, double-blind, tijaabada gawaarida la xakameeyo. Technol Maqaarka 2014 Mee; 20: 208-12. Eeg aragti
11. Khodaeiani E, Fouladi RF, Amirnia M, Saeidi M, Karimi ER. Mawduuca 4% nicotinamide vs. 1% clindamycin ee finanka finanka finanka leh ee vulgaris. Int J Dermatol. 2013 Agoosto; 52: 999-1004. Eeg aragti
12. Janssens GO, Rademakers SE, Terhaard CH, Doornaert PA, Bijl HP, van den Ende P, Chin A, Takes RP, de Bree R, Hoogsteen IJ, Bussink J, Span PN, Kaanders JH. Badbaadinta soo-noqoshada-bilaash la'aanta ee ARCON ee loogu talagalay bukaannada dhiig-yaraanta qaba kansarka hunguriga. Clin Kansarka Res. 2014 Mar 1; 20: 1345-54. Eeg aragti
13. Janssens GO, Rademakers SE, Terhaard CH, Doornaert PA, Bijl HP, van den Ende P, Chin A, Marres HA, de Bree R, van der Kogel AJ, Hoogsteen IJ, Bussink J, Span PN, Kaanders JH. Daaweynta shucaaca ee la dedejiyay oo leh karbogen iyo nicotinamide oo loogu talagalay kansarka laryngeal: natiijooyinka tijaabada wajiga III ee tijaabada ah. J Clin Oncol. 2012 Meey 20; 30: 1777-83. Eeg aragti
14. Fabbrocini G, Cantelli M, Monfrecola G. Cudurka 'nicotinamide' ee loo yaqaan 'seborrheic dermatitis': daraasad furan oo aan kala sooc lahayn. J Daaweynta maqaarka 2014 Juun; 25: 241-5. Eeg aragti
15. Eustace A, Irlam JJ, Taylor J, Denley H, Agrawal S, Choudhury A, Ryder D, Ord JJ, Harris AL, Rojas AM, Hoskin PJ, West CM. Necrosis waxay saadaalisaa inay ka faa'iideysaneyso daaweynta hypoxia-wax ka beddelka daaweynta bukaanka qaba kansarka kaadiheysta ee halista sare leh ee ka diiwaangashan wajiga III tijaabada aan kala sooca lahayn. Radiother Oncol. 2013 Jul; 108: 40-7. Eeg aragti
16. Amengual JE, Clark-Garvey S, Kalac M, Scotto L, Marchi E, Neylon E, Johannet P, Wei Y, Zain J, O’Connor OA. Sirtuin iyo pan-class I / II deacetylase (DAC) xannibaadda ayaa u dhiganta qaababka horudhaca ah iyo daraasadaha bukaan socodka ee lymphoma. Dhiig. 2013 Sep 19; 122: 2104-13. Eeg aragti
17. Shalita AR, Falcon R, Olansky A, Iannotta P, Akhavan A, Day D, Janiga A, Singri P, Kallal JE. Maareynta finanka finanka leh ee kaabista nafaqada ee cusub. J Dawooyinka Dermatol. 2012; 11: 1428-33. Eeg aragti
18. Falsini, B., Piccardi, M., Iarossi, G., Fadda, A., Merendino, E., iyo Valentini, P. Saameynta kaabista antioxidant-ka ee muddada gaaban ee shaqada jirka ee maculopathy-da da'da la xiriirta: daraasad tijaabo ah oo ay ku jiraan qiimeynta elektrofiisiologiga. Cudurka indhaha 2003; 110: 51-60. Eeg aragti
19. Elliott RB, Pilcher CC, Stewart A, Fergusson D, McGregor MA. Isticmaalka nikotinamide ee kahortaga nooca 1aad ee sonkorowga. Ann N Y Acad Sci. 1993; 696: 333-41. Eeg aragti
20. Rottembourg JB, Launay-Vacher V, Massard J. Thrombocytopenia oo ay sababtay nicotinamide bukaanada hemodialysis. Kilyaha Int. 2005; 68: 2911-2. Eeg aragti
21. Takahashi Y, Tanaka A, Nakamura T, et al. Nicotinamide wuxuu xakameynayaa hyperphosphatemia ee bukaanka hemodialysis. Kilyaha Int. 2004; 65: 1099-104. Eeg aragti
22. Soma Y, Kashima M, Imaizumi A, iyo al. Saamaynta qoyaanka ee nikotiinamide la mariyo maqaarka qalalan ee atopic. Int J Dermatol. 2005; 44: 197-202. Eeg aragti
23. Powell ME, Hill SA, Saunders MI, Hoskin PJ, Chaplin DJ. Socodka dhiigga burooyinka bini’aadamka waxaa lagu xoojiyaa neefsiga nicotinamide iyo carbogen. Kansarka Res. 1997; 57: 5261-4. Eeg aragti
24. Hoskin PJ, Rojas AM, Phillips H, Saunders MI. Cudur daran oo soo daahay oo ku dhaca daaweynta kansarka kaadiheysta sare ee leh shucaaca dardargelinta, karbogen, iyo nicotinamide. Kansarka. 2005; 103: 2287-97. Eeg aragti
25. Niren NM, Torok HM. Horumarinta Nicomide ee Daraasaadka Natiijooyinka Caafimaadka (NICOS): natiijooyinka tijaabada toddobaad ee 8. Cutis. 2006; 77 (Qalabka 1): 17-28. Eeg aragti
26. Kamal M, Abbasy AJ, Muslemani AA, Bener A. Saameynta nicotinamide ee carruurta dhowaan la ogaaday nooca 1 ee sonkorowga. Acta Pharmacol Dembi. 2006; 27: 724-7. Eeg aragti
27. Olmos PR, Hodgson MI, Maiz A, et al. Nicotinamide wuxuu ilaaliyay jawaabta insulin wajiga hore (FPIR) waxayna kahortagtay cudurka kiliinikada qaraabada heerka koowaad ee nooca-1 ee sonkorowga. Kalkaalinta Caafimaadka Sonkorowga. 2006; 71: 320-33. Eeg aragti
28. Gale EA, Bingley PJ, Emmett CL, Collier T; Tijaabada Waxka Qabadka Sonkorowga Nicotinamide Sonkorowga (ENDIT). Tijaabada Waxka Qabadka Sonkorowga Nicotinamide (ENDIT): tijaabin la kantaroolay oo la kantaroolay oo faragalin ah kahor bilawga nooca 1aad ee sonkorowga. Lancet. 2004; 363: 925-31. Eeg aragti
29. Cabrera-Rode E, Molina G, Arranz C, Vera M, iyo al. Saameynta heerka caadiga ah ee loo yaqaan 'nicotinamide' ee kahortaga nooca 1aad ee sonkorowga ee ehelka darajada koowaad ee dadka qaba nooca 1aad ee sonkorowga. Isku-kalsoonaanta. 2006; 39: 333-40. Eeg aragti
30. Hakozaki T, Minwalla L, Zhuang J, et al. Saamaynta niacinamide ee yareynta midabka maqaarka iyo xakamaynta wareejinta melanosome. Br J Dermatol. 2002 Jul; 147: 20-31. Eeg aragti
31. Bissett DL, Oblong JE, Berge CA. Niacinamide: Faytamiin B ah oo hagaajiya gabowga muuqaalka maqaarka. Dermatol Surg. 2005; 31 (7 Pt 2): 860-5; dood 865. Eeg aragti.
32. Jorgensen J. Pellagra waxaa laga yaabaa inuu ugu wacan yahay pyrazinamide: horumarka inta lagu guda jiro isku-darka kiimotera ee tiibishada. Int J Dermatol 1983; 22: 44-5. Eeg aragti
33. Swash M, Roberts AH. Cudurka 'encephalopathy' ee loo yaqaan 'pellagra-like encephalopathy' oo leh ethionamide iyo cycloserine. Tubercle 1972; 53: 132. Eeg aragti
34. Brooks-Hill RW, Bishop ME, Vellend H. Pellagra-like encephalopathy oo adkaynaysa dawooyin badan oo loogu talagalay daaweynta cudurka sambabaha sababo la xiriira Mycobacterium avium-intracellulare (warqad). Am Rev Jawaab Dis 1985; 131: 476. Eeg aragti
35. Visalli N, Cavallo MG, Signore A, et al. Tijaabin xarumo badan oo la kala soocay oo ah laba qiyaasood oo kala duwan oo ah nikotiinamide bukaannada qaba nooca sonkorowga 1 ee ugu dambeeyay (IMDIAB VI) Sonkorowga Metab Res Rev 1999; 15: 181-5. Eeg aragti
36. Bourgeois BF, Dodson WE, Ferrendelli JA. Isdhexgalka u dhexeeya primidone, carbamazepine, iyo nicotinamide. Neerfaha 1982; 32: 1122-6. Eeg aragti
37. Papa CM. Niacinamide iyo acanthosis nigricans (warqad). Arch Dermatol 1984; 120: 1281. Eeg aragti
38. Jiilaalka SL, Boyer JL. Sunta cagaarshowga oo ka timaadda qiyaaso badan oo fitamiin B3 ah (nicotinamide). N Engl J Med 1973; 289: 1180-2. Eeg aragti
39. McKenney J. Aragtiyo cusub oo ku saabsan isticmaalka niacin ee daaweynta xanuunnada dufanka. Arch Intern Med 2004; 164: 697-705. Eeg aragti
40. Kordhinta HDL iyo Niacin Use. Warqadda Farmashiistaha / Waraaqaha Qoraha 2004; 20: 200504.
41. Hoskin PJ, Stratford MR, Saunders MI, iyo al. Maamulka nicotinamide inta lagu jiro jaantuska: farmasokokinetics, kordhinta qiyaasta, iyo sunta daaweynta. Int J Radiat Oncol Biol Phys 1995; 32: 1111-9. Eeg aragti
42. Fatigante L, Ducci F, Cartei F, et al. Carbogen iyo nicotinamide oo ay weheliso shucaac aan caadi ahayn oo loo yaqaan 'glioblastoma multiforme': daaweyn hab cusub ah. Int J Radiat Oncol Biol Phys 1997; 37: 499-504. Eeg aragti
43. Miralbell R, Mornex F, Greiner R, iyo al. Daaweynta shucaaca ee la dedejiyey, karbogen, iyo nicotinamide ee glioblastoma multiforme: warbixinta Ururka Yurub ee Cilmi baarista iyo Daaweynta Kansarka tijaabada 22933. J Clin Oncol 1999; 17: 3143-9. Eeg aragti
44. Anon. Niacinamide Monograph. Alt Med Rev 2002; 7: 525-9. Eeg aragti
45. Haslam RH, Dalby JT, Rademaker AW. Saamaynta daaweynta loo yaqaan 'megavitamin therapy' ee carruurta leh cilladaha maqnaanshaha. Dhakhaatiirta carruurta 1984; 74: 103-11 .. Eeg duluc.
46. Guddiga Cuntada iyo Nafaqada, Machadka Daawada. Tixraacyada Cunnooyinka ee loo qaato Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, iyo Choline. Washington, DC: National Academy Press, 2000. Waxaa laga heli karaa: http://books.nap.edu/books/0309065542/html/.
47. Shalita AR, Smith JG, Parish LC, et al. Cudurka 'nicotinamide' marka la barbardhigo gelka clindamycin ee daaweynta finanka finanka vulgaris. Int J Dermatol 1995; 34: 434-7. Eeg aragti
48. McCarty MF, Russell AL. Daaweynta Niacinamide ee loo yaqaan 'osteoarthritis' - miyuu joojiyaa nitric oxide synthase induction by interleukin 1 ee chondrocytes? Faallooyin Med ah 1999; 53: 350-60. Eeg aragti
49. Jonas WB, Rapoza CP, Blair WF. Saamaynta niacinamide ee osteoarthritis: daraasad tijaabo ah. Cadaadiska Dhibaatada 1996; 45: 330-4. Eeg aragti
50. Polo V, Saibene A, Pontiroli AE. Nicotinamide waxay hagaajineysaa dheecaanka insulin-ta iyo xakameynta dheef-shiid kiimikaadka nooca bukaanka 2 ee sonkorowga qaba oo leh guuldaradii labaad ee sulphonylureas. Acta Diabetol 1998; 35: 61-4. Eeg aragti
51. Greenbaum CJ, Kahn SE, Palmer JP. Saamaynta Nicotinamide ee ku saabsan dheef-shiid kiimikaadka maadooyinka halista ugu jira IDDM. Sonkorowga 1996; 45: 1631-4. Eeg aragti
52. Pozzilli P, Browne PD, Kolb H. Meta-falanqaynta daaweynta nikotinamide ee bukaanada leh IDDM-da dhowaan bilaabmay. Tijaabiyeyaasha Nicotinamide. Daryeelka Sonkorowga 1996; 19: 1357-63. Eeg aragti
53. Pozzilli P, Visalli N, Signore A, et al. Tijaabinta indho la'aanta ah ee nikotiinamide ee dhowaan bilawday IDDM (daraasadda IMDIAB III). Diabetologia 1995; 38: 848-52. Eeg aragti
54. Visalli N, Cavallo MG, Signore A, et al. Tijaabin xarumo badan oo la kala soocay oo ah laba qiyaasood oo kala duwan oo ah nikotiinamide bukaannada qaba nooca sonkorowga 1 ee ugu dambeeyay (IMDIAB VI) Sonkorowga Metab Res Rev 1999; 15: 181-5. Eeg aragti
55. Pozzilli P, Visalli N, Cavallo MG, et al. Faytamiin E iyo nicotinamide waxay leeyihiin saameyn isku mid ah sii wadida shaqeynta unugyada beta ee hadhaagii ugu dambeeyay bilawga cudurka sonkorowga ee ku tiirsan insulin-ta. Eur J Endocrinol 1997; 137: 234-9. Eeg aragti
56. Lampeter EF, Klinghammer A, Scherbaum WA, iyo al. Daraasadda Faragelinta Deutsche Nicotinamide: isku day ah in laga hortago nooca 1aad ee sonkorowga. Kooxda DENIS. Sonkorowga 1998; 47: 980-4. Eeg aragti
57. Elliott RB, Pilcher CC, Fergusson DM, Stewart AW. Istaraatijiyad ku saleysan dadweynaha si looga hortago sonkorowga ku-tiirsan insulin iyadoo la adeegsanayo nikotinamide. J Pediatr Endocrinol Metab 1996; 9: 501-9. Eeg aragti
58. Gale EA. Aragtida iyo ku dhaqanka tijaabooyinka nikotiinamide ee nooca sonkorowga nooca 1-aad. J Pediatr Endocrinol Metab 1996; 9: 375-9. Eeg aragti
59. Kolb H, Burkart V. Nicotinamide nooca 1aad ee sonkorowga. Farsamaynta waxqabadka ayaa dib loo eegay. Daryeelka Sonkorowga 1999; 22: B16-20. Eeg aragti
60. Bulshada Mareykanka ee Farmashiyeyaasha Nidaamka Caafimaadka. Qoraalka Jagada Daaweynta ee ASHP ee ku saabsan isticmaalka nabdoon ee niacin ee maareynta dyslipidemias. Am J Caafimaadka Syst Pharm 1997; 54: 2815-9. Eeg aragti
61. Garg A, Grundy SM. Nicotinic acid sida daaweynta dyslipidemia ee sonkorowga mellitus-ku-tiirsan insulin-ta. JAMA 1990; 264: 723-6. Eeg aragti
62. Crouse JR III. Isbedelada cusub ee isticmaalka niacin ee daaweynta hyperlipidemia: tixgelinta cusub ee isticmaalka daroogada duugga ah. Coron Artery Dis 1996; 7: 321-6. Eeg aragti
63. Brenner A. Saameynta megadoses ee fiitamiinada isku-dhafan ee B ee la xushay ee carruurta leh hyperkinesis: daraasado la xakameeyey oo dabagal dheer ah. J Baro Disabil 1982; 15: 258-64. Eeg aragti
64. Yates AA, Schlicker SA, Suitor CW. Tixraacyada tixraaca cuntada: Saldhigga cusub ee talooyinka loogu talagalay kaalshiyamka iyo nafaqooyinka la xiriira, fiitamiinnada B, iyo choline. J Am Cuntada Assoc 1998; 98: 699-706. Eeg aragti
65. Shils ME, Olson JA, Shike M, Ross AC, eds. Nafaqada casriga ah ee caafimaadka iyo cudurada. 9aad. Baltimore, MD: Williams & Wilkins, 1999.
66. Harvengt C, Desager JP. HDL-kolestaroolka ayaa kordha maadooyinka 'normolipaemic' ee khellin: daraasad tijaabo ah. Int J Clin Pharmacol Qaraarka 1983; 3: 363-6. Eeg aragti
67. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman iyo Gillman's Aasaaska Farmasiga ee Daaweynta, 9aad ed. New York, NY: McGraw-Hill, 1996.
68. McEvoy GK, ed. Macluumaadka Dawooyinka AHFS. Bethesda, MD: Bulshada Mareykanka ee Farmashiistayaasha Nidaamka Caafimaadka, 1998.
69. Blumenthal M, ed. Komishanka Jarmalka oo Dhamaystiran E Monographs: Tilmaamaha Daaweynta ee Daawooyinka Dhirta. Trans. S. Klein. Boston, MA: Golaha Botaniga Mareykanka, 1998.

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