Qoraa: William Ramirez
Taariikhda Abuurista: 19 Setembar 2021
Taariikhda Cusboonaysiinta: 13 Noofeembar 2024
Anonim
Spironolactone and drug-resistant hypertension - Video Review
Dareemoleyad: Spironolactone and drug-resistant hypertension - Video Review

Qanacsan

Spironolactone wuxuu sababay burooyin ku dhaca xayawaanka shaybaarka. Kala hadal dhakhtarkaaga khataraha iyo faa'iidooyinka isticmaalka daawadan ee xaaladdaada.

Spironolactone waxaa loo isticmaalaa in lagu daaweeyo bukaanada qaarkood ee leh hyperaldosteronism (jirku wuxuu soo saaraa aldosterone aad u badan, hormoon dabiici ah oo ku dhaca); heerarka potassium ee hooseeya; wadnaha oo istaaga; iyo bukaanka qaba barar (dheecaan haynta) oo ay keeneen xaalado kala duwan, oo ay ku jiraan beerka, ama cudurka kalyaha. Waxaa sidoo kale loo isticmaalaa kali ama daawooyin kale si loogu daaweeyo dhiig karka. Spironolactone waxay ku jirtaa nooc dawooyin ah oo loo yaqaan 'aldosterone receptor antagonists'. Waxay ku keentaa kilyaha inay ka baabi'iyaan biyaha aan loo baahnayn iyo soodhiyamka jidhka ku jira kaadida laakiin waxay yareeysaa luminta jirka ee jirka.

Dhiig karka waa xaalad caadi ah oo marka aan la daweynin, wuxuu dhaawac u geysan karaa maskaxda, wadnaha, xididdada dhiigga, kilyaha iyo qeybaha kale ee jirka. Dhaawaca xubnahan waxay sababi karaan wadno xanuun, wadno istaag, wadnaha oo istaaga, istaroog, howlgab kilyaha, araga oo luma, iyo dhibaatooyin kale. Qaadashada daawada ka sokoow, sameynta isbeddelka hab-nololeedka waxay sidoo kale kaa caawin doontaa inaad xakameyso cadaadiska dhiiggaaga. Isbeddeladan waxaa ka mid ah cunista cunto dufan iyo milix ku yar tahay, joogteynta culeys caafimaad leh, jimicsi ugu yaraan 30 daqiiqo inta badan maalmaha, sigaar cabidda, iyo isticmaalka qamriga oo dhexdhexaad ah.


Spironolactone wuxuu u yimaadaa kiniin ahaan iyo ganaax (dareere; Carospir) si afka looga qaato. Badanaa waxaa la qaataa hal ama laba jeer maalintii. Qaado hakinta spironolactone si isdaba joog ah ha ahaato cunto ama cunto la'aan markasta. Qaado daawada loo yaqaan 'spironolactone' qiyaastii isla waqtigaas (maalin kasta). Si taxaddar leh u raac tilmaamaha ku qoran calaamadaha laguu qoray, oo weydii takhtarkaaga ama farmashiistaha inuu kuu sharxo qayb kasta oo aadan fahmin. Qaado spironolactone sida saxda ee lagu faray. Ha ka qaadin wax ka yar ama ka yar ama u qaado si ka badan inta dhakhtarku kuu qoray.

Si fiican u rux joojinta afka si aad u isticmaasho ka hor intaan la istcimaalin.

Dhakhtarkaagu wuxuu kugu bilaabi karaa qadar yar oo ah 'spironolactone' wuxuuna si tartiib tartiib ah u kordhiyaa qiyaastaada.

Kiniiniyada 'Spironolactone' iyo ganaax ayaa daawada u siideeya si ka duwan jirkaaga lagumana beddeli karo midba midka kale. Kaliya qaado badeecada loo yaqaan 'spironolactone' oo uu dhakhtarkaagu kuu qoray oo ha u wareegin badeecad kale oo ah 'spironolactone' haddii uusan dhakhtarkaagu kuu sheegin inaad sidaas sameyso.


Spironolactone wuxuu xakameynayaa dhiig karka, bararka, wadnaha oo istaaga, iyo hyperaldosteronism laakiin ma daaweynayo xaaladahan. Waxay qaadan kartaa qiyaastii 2 toddobaad ama ka badan intaan waxtarka buuxa ee spironolactone uusan dhicin. Sii wad inaad qaadato daawada loo yaqaan 'spironolactone' xitaa haddii aad fiicnaan dareento. Ha u joojin daawada loo yaqaan 'spironolactone' adiga oo aan la hadlin dhakhtarkaaga.

Spironolactone sidoo kale waxaa loo isticmaalaa dawooyin kale oo lagu daaweeyo qaangaadhnimada (xaalad u horseedaysa carruurta inay si dhakhso leh u galaan baaluqnimo, taasoo keenta horumarinta astaamaha galmada ee gabdhaha inta badan ka yar da'da 8 sano iyo wiilasha inta badan ka yar da'da 9 da'da. ) ama myasthenia gravis (MG, oo ah cudur dareemayaasha aysan si sax ah u shaqeynin oo bukaanku la kulmi karo daciifnimo; kabuubyo, luminta isku xirnaanta muruqyada; iyo dhibaatooyinka aragga, hadalka, iyo kaadiheysta xakameynta). Spironolactone sidoo kale waxaa loo isticmaali karaa in lagu daaweeyo bukaanjiifka dumarka qaarkood ee leh timaha wajiga oo aan caadi ahayn. Kala hadal dhakhtarkaaga khataraha suurtagalka ah ee u isticmaalka daawadan xaaladdaada.


Daawadan ayaa mararka qaarkood loo qoraa adeegsiyo kale; Weydii dhakhtarkaaga ama farmashiistaha wixii macluumaad dheeraad ah.

Kahor qaadashada daawada loo yaqaan 'spironolactone',

  • u sheeg dhakhtarkaaga iyo farmashiistaha haddii aad xasaasiyad ku leedahay spironolactone; daawooyin kale; ama mid ka mid ah maaddooyinka ku jira kiniiniyada 'spironolactone'. Weydii farmashiistahaaga liiska waxyaabaha ay ka kooban yihiin.
  • u sheeg dhakhtarkaaga haddii aad qaadanayso eplerenone (Inspra). Dhakhtarkaagu wuxuu kuu sheegi karaa inaadan qaadan spironolactone haddii aad qaadanaysid dawadan.
  • u sheeg dhakhtarkaaga iyo farmashiistaha dawooyinka dhakhtarku qoro iyo kuwa aan dhakhtar qorin, fiitamiinnada, nafaqada nafaqada, iyo alaabta dhirta ah ee aad qaadanayso ama aad qorsheyneyso inaad qaadato. Hubso inaad sheegto mid ka mid ah kuwan soo socda: antibiyootikada aminoglycoside sida amikacin, gentamicin, kanamycin, neomycin (Neo-Rx, Neo-Fradin), streptomycin, iyo tobramycin (Tobi); angiotensin-converting enzyme (ACE) inhibitors sida benazepril (Lotensin, in Lotrel), captopril (Capoten), enalapril (Vasotec), fosinopril, lisinopril (Prinzide, Zestoretic), moexipril (Univasc, Uniretic), perind Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), iyo trandolapril (Mavik, in Tarka); angiotensin II antagonists (angiotensin receptor blockers; ARBs) sida azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten, in Teveten HCT), irbesartan (Avapro, in Avalide), losartan (Cozaar, in in Hyzaar), olmesartan (Benicar, Azor, Benicar HCT, Tribenzor), telmisartan (Micardis, Micardis HCT) iyo valsartan (Diovan, Diovan HCT, Exforge); aspirin iyo dawooyinka kale ee non-steroid anti-inflammatory (NSAIDS) sida ibuprofen (Advil, Motrin), indomethacin (Indocin, Tivorbex), iyo naproxen (Aleve, Naprosyn); barbiturates sida phenobarbital; cholestyramine (Prevalite); cisplatin; digoxin (Lanoxin); diuretics ('kaniiniyada biyaha') oo ay kujiraan diuretics-ka ilaaliya jirka sida amiloride (Midamor) iyo triamterene (Dyrenium, in Dyazide, in Maxzide); heparin ama miisaan-yar oo culeys-heparin enoxaparin (Lovenox); lithium (Lithobid); daawooyinka lagu daaweeyo dhiig karka; daawooyinka daroogada ee xanuunka; steroids-ka afka laga qaato sida dexamethasone, methylprednisolone (Medrol), iyo prednisone (Rayos); kaalshiyamta; iyo trimethoprim (Primsol, gudaha Bactrim).
  • u sheeg dhakhtarkaaga haddii aad qabtid cudurka Addison ama xaalado kale oo sababi kara heerar sare oo dhiig oo ah macdanta potassium, ama cudurka kalyaha. Dhakhtarkaaga ayaa laga yaabaa inuu kuu sheego inaadan qaadan spironolactone.
  • u sheeg dhakhtarkaaga haddii aad qabto cudur beerka ah.
  • u sheeg dhakhtarkaaga haddii aad uur leedahay, ama aad qorsheyneyso inaad uur yeelato, ama aad naas nuujiso. Haddii aad uur yeelato inta aad qaadanaysid daawada loo yaqaan 'spironolactone', wac dhakhtarkaaga.
  • haddii aad qalliin samaynayso, oo ay ku jiraan qalliinka ilkaha, u sheeg dhakhtarka ama dhakhtarka ilkaha inaad qaadanayso dawada loo yaqaan 'spironolactone'.
  • waa inaad ogaataa in khamriga lagu cabbo daawadan ay sababi karto dawakhaad, madax-wareer, iyo miyir beel markii aad dhaqso uga kacdid jiifka. Kala hadal dhakhtarkaaga wax ku saabsan cabitaanka aalkolada inta aad qaadanaysid daawada loo yaqaan 'spironolactone'.

Raac tilmaamaha dhakhtarkaaga ee cuntadaada, oo ay ku jiraan talobixinta cuntada milixdu ku yar tahay (sodium) iyo barnaamijka jimicsiga maalinlaha ah. Ka fogow beddelka milixda ay ku jirto macdanta potassium inta aad qaadanaysid dawadan. Kala hadal dhakhtarkaaga xaddiga cuntooyinka ay ku badan tahay macdanta potassium (tusaale, muuska, goosato, sabiib, iyo casiirka liinta) ee laga yaabo inaad ku jirto cuntadaada.

Qaado qiyaasta la seegay isla marka aad xasuusatoba. Si kastaba ha noqotee, haddii ay ku dhowdahay waqtiga qiyaastaada xigta, ka bood qiyaasta la seegay oo sii wad jadwalkaaga qiyaasta daawada ee caadiga ah. Ha qaadan laba-qaadasho si aad uhesho mid kaa dhaafay.

Spironolactone waxay sababi kartaa waxyeelo. U sheeg dhakhtarkaaga haddii mid ka mid ah astaamahani ay daran yihiin ama aanad tagin:

  • matagid
  • shuban
  • calool xanuun ama casiraad
  • naasaha oo weynaaday ama xanuun badan ragga ama dumarka
  • caadada oo aan caadi ahayn
  • dhiig bax siilka ka dib caadada ka dib ('isbadalka nolosha kadib', dhamaadka caadada billaha ah) dumarka
  • Dhibaato sii wadida ama ku guuleysiga kacsiga
  • sii xoojinta codka
  • kordhinta koritaanka timaha ee qaybaha jirka
  • lulmid
  • daallan
  • degganaansho la'aan

Dhibaatooyinka qaarkood waxay noqon karaan kuwo halis ah. Haddii aad isku aragto mid ka mid ah astaamahan, wac dhakhtarkaaga isla markiiba:

  • murqaha oo daciifa, xanuun, ama casiraad
  • xanuun, gubasho, kabuubyo, ama xoqid gacmaha ama cagaha
  • awoodin dhaqaaqa gacmaha ama lugaha
  • isbedelada garaaca wadnaha
  • jahwareer
  • lallabbo
  • daal xad dhaaf ah
  • afka qalalan, harraad, dawakhaad, deganaan la'aan, madax xanuun, ama calaamadaha kale ee fuuqbaxa
  • dhiigbax ama nabar aan caadi ahayn
  • tamar la’aan
  • cunto xumo
  • xanuun qeybta kore ee midig ee caloosha
  • hurdi maqaarka ama indhaha
  • astaamaha hargabka oo kale ah
  • finan
  • finan
  • cuncun
  • neefsashada ama wax liqidda oo ku adkaata
  • matag dhiig
  • dhiig saxarada ku jira
  • kaadida oo yaraatay
  • miyir beelid

Haddii aad isku aragto waxyeellooyin daran, adiga ama dhakhtarkaaga ayaa warbixin u diri kara Barnaamijka Ka Warbixinta Dhacdooyinka Xun ee Maamulka Cuntada iyo Dawooyinka (FDA) (http://www.fda.gov/Safety/MedWatch) ama taleefan ( 1-800-332-1088).

Daawadan ku hay weelka ay soo gashay, si adag u xir, oo ka fog carruurta. Ku keydi heerkulka qolka oo ka fog kuleylka iyo qoyaanka badan (ha ku jirin musqusha).

Waa muhiim inaad ka ilaaliso dhammaan daawooyinka meel aan la arkeynin oo aysan gaari karin carruurta maaddaama weelal badan (sida kuwa toddobaadlaha kiniiniga ka fiirsada iyo kuwa loogu talagalay dhibcaha isha, kareemada, dhejiyeyaasha, iyo kuwa neefta ku siiya) uma adkeysana carruurta, carruurta yaryarna si fudud ayey ku furi karaan. Si aad uga ilaaliso carruurta yaryar sunta, marwalba xiro daboolka badbaadada isla markaana isla markiiba dhig dawada meel aamin ah - mid kor iyo fog kana fog aragooda oo gaadha. http://www.upandaway.org

Daawooyinka aan loo baahnayn waa in lagu tuuraa siyaabo gaar ah si loo hubiyo in xayawaanka, carruurta, iyo dadka kaleba aysan cuni karin. Si kastaba ha noqotee, waa inaadan ku daadinin daawadan musqusha hoosteeda. Taabadalkeed, sida ugufiican ee dawada looga takhalusi karaa waa iyada oo loo maro barnaamijka dib u celinta daawada. La hadal farmashiistahaaga ama la xiriir waaxda qashinka / dib u warshadaynta si aad wax uga ogaato barnaamijyada dib-u-celinta ee bulshadaada. Ka eeg bogga internetka ee 'FDA ee Amni-Qaadashada Daawooyinka (http://goo.gl/c4Rm4p) si aad u hesho macluumaad dheeraad ah haddii aadan marin u helin barnaamijka dib-u-celinta.

Xaalada xad dhaafka ah, wac khadka caawinta ka hortagga sunta 1-800-222-1222. Macluumaadka sidoo kale waxaa laga heli karaa internetka https://www.poisonhelp.org/help. Haddii dhibbanuhu burburay, suuxdin qabtay, neefsashadu dhib ku tahay, ama aan la kici karin, isla markiiba wac adeegyada gurmadka ee 911.

Calaamadaha xad-dhaafka ah waxaa ka mid noqon kara kuwa soo socda:

  • lulmid
  • jahwareer
  • finan
  • lallabbo
  • matagid
  • dawakhaad
  • shuban
  • gacmaha iyo lugaha oo la ruxruxo
  • luminta muruqyada
  • daciifnimo ama culeys lugaha ah
  • wadnaha oo aan caadi ahayn ama gaabis ah

Dhammaan ballamaha la dhig dhakhtarkaaga iyo shaybaarka. Dhakhtarkaagu wuxuu amri doonaa tijaabooyinka shaybaarka qaarkood si loo hubiyo jawaabta jirkaaga ee spironolactone.

Kahor baaritaanka shaybaarka, u sheeg dhakhtarkaaga iyo shaqaalaha sheybaarka inaad qaadanayso spironolactone.

Ha u ogolaan qof kale inuu qaato daawadaada. Weydii farmashiistahaaga wixii su'aalo ah ee aad ka qabto dib u soo celinta daawada laguu qoray.

Waxaa muhiim kuu ah inaad haysato liis qoran oo ku saabsan dhammaan daawooyinka laguu qoro iyo kuwa aan dhakhtar qorin (warqad dhakhtar la aan ah) ee aad qaadanaysid, iyo sidoo kale wax soo saar kasta sida fiitamiinnada, macdanta, ama nafaqooyinka kale ee nafaqada leh. Waa inaad soo qaadataa liiskan markasta oo aad booqato dhakhtar ama haddii isbitaal la dhigo. Sidoo kale waa macluumaad muhiim ah inaad lasocoto haddii ay jiraan xaalado deg deg ah.

  • Aldactone®
  • Carospir®
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