Tijaabada Hormone Anti-Müllerian

Qanacsan

• Waa maxay baaritaanka anti-m -llerian hormone (AMH)?
• Maxaa loo adeegsadaa?
• Maxaan ugu baahanahay baaritaanka AMH?
• Maxaa dhacaya inta lagu jiro baaritaanka AMH?
• Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?
• Ma jiraan wax khatar ah oo imtaxaanku leeyahay?
• Maxay natiijooyinka ka dhigan yihiin?
• Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka AMH?
• Tixraacyo

Waa maxay baaritaanka anti-m -llerian hormone (AMH)?

Tijaabadani waxay cabireysaa heerka hoormoonka anti-müllerian (AMH) ee dhiiga. AMH waxaa lagu sameeyay unugyada taranka ee labka iyo dheddigga. Doorka AMH iyo inay heerarku caadi yihiin waxay kuxirantahay da'daada iyo jinsigaaga.

AMH waxay door muhiim ah ka ciyaartaa horumarinta xubnaha galmada ee ilmaha aan dhalan. Toddobaadyada ugu horreeya uurka, ilmuhu wuxuu bilaabi doonaa inuu sameeyo xubnaha taranka. Ilmuhu wuxuu hore u yeelan doonaa hiddo-wadaha noqon kara lab (hiddo-wadaha XY) ama dheddig (hiddo-wadaha XX).

Haddii ilmuhu leeyahay hiddo-wadaha lab (XY), heerarka sare ee AMH ayaa la sameeyaa, oo ay weheliyaan hormoonno kale oo lab ah. Tani waxay ka hortageysaa horumarinta xubnaha dumarka waxayna kobcineysaa sameynta xubnaha labka. Haddii aysan ku filneyn AMH inay joojiso horumarinta xubnaha haweenka, xubnaha labada jinsi ayaa soo bixi kara. Markay tani dhacdo, xubnaha taranka ilmaha si cad looma aqoonsan karo inay yihiin lab ama dhadig. Tan waxaa looyaqaanaa xubinta taranka ee madmadaw. Magaca kale ee xaaladdan waa intersex.

Haddii ilmaha caloosha ku jira uu leeyahay hiddo-wadaha dhadig (XX) qadar yar oo AMH ah ayaa la sameeyaa. Tani waxay u oggolaaneysaa horumarinta xubnaha taranka haweenka. AMH waxay leedahay door ka duwan dumarka marka ay qaan gaaraan. Waqtigaas, ugxan sidaha (qanjidhada sameeya unugyada ukunta) waxay bilaabaan sameynta AMH. Tirada ukunta oo badan ayaa jirta, heerka sare ee AMH.

Haweenka, heerarka AMH waxay bixin karaan macluumaad kusaabsan bacriminta, awooda uur yeelashada. Baaritaanka waxaa sidoo kale loo isticmaali karaa in lagu caawiyo baaritaanka cilladaha caadada ama in lala socdo caafimaadka dumarka qaba noocyo ka mid ah kansarka ugxansidaha ugxan sidaha.

Magacyada kale: baaritaanka hormoonka AMH, hormoonka müllerian-inhibiting, MIH, cunsuriyada müllerian, MIF, walaxda müllerian-inhibiting, MIS

Maxaa loo adeegsadaa?

Baadhitaanka AMH waxaa badanaa loo isticmaalaa in lagu hubiyo awoodda haweeneyda ee ah soo saarista ukumo la bacrimin karo uurka. Ukunta haweeneydu waxay sameyn kartaa kumanaan ukun ah sannadaha ay dhaleyso. Tirada ayaa hoos u dhacday markii haweeneydu sii weynaato. Heerarka AMH waxay gacan ka geystaan ​​muujinta inta unugyo ugxan ah oo haween ah ay ku hartay. Tan waxaa loo yaqaanaa keydka ugxansidaha.

Haddii keydka ugxansidaha ee haweenku sarreeyo, waxaa laga yaabaa inay fursad fiican u yeelato uur. Waxa kale oo laga yaabaa inay sugto bilo ama sannado ka hor isku dayga inay uur qaado. Haddii keydka ugxantu hooseeyo, waxaa laga yaabaa inay macnaheedu tahay haweeney inay dhibaato kala kulmi doonto uur qaadista, waana inaysan dib u dhigin waqti aad u dheer ka hor isku dayga inay ilmo dhasho

Imtixaanada AMH sidoo kale waxaa loo isticmaali karaa:

• Saadaal bilowga caadada, waqtiga nolosha haweeneyda oo caadadadeedii istaagtay oo aysan mar dambe uur qaadi karin. Badanaa wuxuu bilaabmaa markay haweeneydu gaarto qiyaastii 50 sano.
• Soo ogow sababta dhalmo dayska hore
• Caawinaad ka hel sidii loo ogaan lahaa sababaha loo yaqaan amenorrhea, caado la'aanta. Badanaa waxaa lagu ogaadaa gabdhaha aan bilaabin caadada da'da 15 iyo dumarka seegay dhowr jeer.
• Caawinta baaritaanka cudurka polycystic ovary syndrome (PCOS), cilad hormoon taas oo ah sababaha guud ee dhalmo la'aanta dumarka, awood la'aanta in uur la yeesho
• Ka hubi dhallaanka xubnaha taranka ee aan si cad loogu aqoonsan inay yihiin lab ama dhadig
• La soco haweenka qaba noocyada kansarka ugxan-sidaha

Maxaan ugu baahanahay baaritaanka AMH?

Waxaad u baahan kartaa baaritaanka AMH haddii aad tahay haweeney ay dhibaato ku tahay uurka. Baaritaanku wuxuu kaa caawin karaa inaad muujiso fursadahaaga uur qaadista cunug. Haddii aad horeba u aragtay takhtar ku takhasusay bacriminta, dhakhtarkaagu wuxuu u adeegsan karaa baaritaanka si loo saadaaliyo inaad sifiican ugajawaabi doonto daaweynta, sida in vitro fertilisation (IVF).

Heerarka sare ayaa laga yaabaa inay la micno tahay inaad heli karto ukumo badan oo si fiican uga jawaab celin doona daaweynta. Heerarka hoose ee AMH waxay la macno tahay inaad yeelan karto ukumo kayar oo aad heli karto lagamana yaabo inaad sifiican uga jawaabto daaweynta.

Waxaad sidoo kale u baahan kartaa baaritaanka AMH haddii aad tahay qof dumar ah oo leh astaamo cudurka polycystic ovary syndrome (PCOS). Kuwaas waxaa ka mid ah:

• Ciladaha caadada, oo ay kujiraan caadad joojinta hore ama amenorrhea
• Finanka
• Kordhinta timaha jirka iyo wejiga
• Cabirka naaska oo yaraaday
• Miisaanka oo kordha

Intaas waxaa sii dheer, waxaad u baahan kartaa baaritaanka AMH haddii lagaa daweynayo kansarka ugxan sidaha. Tijaabadu waxay kaa caawin kartaa inaad muujiso haddii daweyntaadu shaqaynayso.

Maxaa dhacaya inta lagu jiro baaritaanka AMH?

Xirfadlaha daryeelka caafimaadka ayaa tijaabo dhiig ka qaadi doona xididka gacantaada, isagoo isticmaalaya cirbad yar. Kaddib cirbada la geliyo, qadar yar oo dhiig ah ayaa lagu ururin doonaa tuubada baaritaanka ama fijaan. Waxaa laga yaabaa inaad dareento xoog wax yar ah markii irbadda ay soo galayso ama ay ka baxeyso. Tani badanaa waxay qaadataa in ka yar shan daqiiqo.

Ma u baahanahay inaan sameeyo wax walba si aan ugu diyaargaroobo imtixaanka?

Uma baahnid wax diyaargarow gaar ah oo loogu talagalay imtixaanka AMH.

Ma jiraan wax khatar ah oo imtaxaanku leeyahay?

Khatar aad u yar baa jirta in dhiig lagaa qaado. Waxaa laga yaabaa inaad xanuun yar ama nabar ku yeelato barta irbadda lagu muday, laakiin astaamaha badankood si dhakhso leh ayey u baxaan.

Maxay natiijooyinka ka dhigan yihiin?

Haddii aad tahay haween isku dayaysa inaad uur yeelato, natiijooyinkaaga ayaa kaa caawin kara inaad muujiso fursadahaaga uur qaadista. Waxay sidoo kale kaa caawin kartaa inaad go'aansato goorta la isku dayo inaad uur yeelato. Heerka sare ee AMH wuxuu macnaheedu noqon karaa in fursadahaagu fiicnaadaan waxaana laga yaabaa inaad waqti badan hesho kahor isku dayga inaad uur yeelato.

Heerka sare ee AMH wuxuu kaloo macnaheedu noqon karaa inaad leedahay cillad ugxansidaha ugxansidaha ee loo yaqaan 'polycystic ovary syndrome' (PCOS). PCOS daawo maleh, laakiin astaamaha waxaa lagu maamuli karaa daawooyin iyo / ama isbeddelada qaab nololeedka, sida ilaalinta cunno caafimaad qabta iyo xoqista ama xiirashada si looga saaro timaha jirka ee xad dhaafka ah

Heer hoose wuxuu macnaheedu noqon karaa inaad dhibaato ku qabtid uur qaadista. Waxay kaloo macnaheedu noqon kartaa inaad bilaabayso caadada. Heer hoose oo AMH ah ayaa caadi ku ah gabdhaha da'da yar iyo dumarka dhalmo-dayska ka dib.

Haddii lagaa daweynayo kansarka ugxan sidaha, baaritaankaagu wuxuu muujin karaa in daaweyntaadu shaqeynayso iyo in kale.

Ilmaha labka ah, heerka hoose ee AMH wuxuu macnaheedu noqon karaa dhibaato hidde iyo / ama hoormoon sababaya xubnaha taranka oo aan si cad u ahayn lab ama dhadig. Haddii heerarka AMH ay caadi yihiin, waxaa laga yaabaa inay micnaheedu tahay in canugga uu leeyahay xiniinyaha shaqeeya, laakiin kuma jiraan meesha saxda ah. Xaaladdan waxaa lagu daaweyn karaa qalliin iyo / ama daaweynta hoormoonka.

Haddii aad su'aalo ka qabtid natiijooyinkaaga, la hadal daryeel caafimaad bixiyahaaga.

Wax badan ka baro baaritaanka shaybaarka, kala duwanaanshaha tixraaca, iyo fahamka natiijooyinka.

Ma jiraan wax kale oo aan u baahanahay inaan ka ogaado baaritaanka AMH?

Haddii aad tahay haween laga daweynayo dhibaatooyinka bacriminta, waxaad u badan tahay in lagaa qaadi doono baaritaanno kale, oo ay weheliso AMH. Kuwaas waxaa ka mid ah baaritaanka estradiol iyo FSH, labo hoormoon oo ku lug leh taranka.

Tixraacyo

1. Carmina E, Fruzzetti F, Lobo RA. Kordhinta heerarka hormoonka anti-Mullerian iyo cabbirka ugxan sidaha ee koox hoosaad ka mid ah haweenka oo leh howl-qabad hypothalamic amenorrhea: aqoonsi dheeri ah oo ku saabsan xiriirka ka dhexeeya polycystic ovary syndrome iyo hypothalamic amenorrhea shaqeynaya. Am J Obstet Gynecol [Internet]. 2016 Jun [daliishaday 2018 Dec 11]; 214 (6): 714.e1-714.e6. Waxaa laga heli karaa: https://www.ncbi.nlm.nih.gov/pubmed/26767792
2. Xarunta Daawada Taranka (Internetka). Houston: MadhalaysnimadaTexas.com; c2018. Imtixaanka AMH; [daliishaday 2018 Dec 11]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.infertilitytexas.com/amh-testing
3. Grynnerup AG, Lindhard A, Sørensen S. Doorka hormoonka anti-Müllerian ee taranka haweenka iyo madhalaysnimada-guudmar. Fadeexada Acta Obstet [Internet]. 2012 Nov [daliishaday 2018 Dec 11]; 91 (11): 1252-60. Waxaa laga heli karaa: https://www.ncbi.nlm.nih.gov/pubmed/22646322
4. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington D.C; Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2018. Hormoonka kahortaga Müllerian; [cusbooneysiiyay 2018 Sep 13; daliishaday 2018 Dec 11; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/tests/anti-mullerian-hormone
5. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington D.C; Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2018. Caaddo-dayska; [cusbooneysiiyay 2018 Meey 30; daliishaday 2018 Dec 11]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/conditions/menopause
6. Tijaabooyinka Shaybaarka ee Internetka [Internetka] Washington D.C; Ururka Mareykanka ee Kiimikada Caafimaadka; c2001–2018. Cudurka Polycystic Ovary Syndrome; [cusbooneysiiyay 2018 Oct 18; daliishaday 2018 Dec 11; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://labtestsonline.org/conditions/polycystic-ovary-syndrome
7. Mayo Clinic [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. Amenorrhea: Astaamaha iyo sababaha; 2018 Apr 26 [daliishaday 2018 Dec 11]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.mayoclinic.org/diseases-conditions/amenorrhea/symptoms-causes/syc-20369299
8. Mayo Clinic [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. Bacriminta fitamiinada (IVF): Ku saabsan; 2018 Mar 22 [daliishaday 2018 Dec 11]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.mayoclinic.org/tests-procedures/in-vitro-fertilization/about/pac-20384716
9. Mayo Clinic [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1998–2018. Xiniinyaha aan la cayimin: Ciladda iyo daaweynta; 2017 Aug 22 [daliishaday 2018 Dec 11]; [ilaa 4 shaashadood]. Waxaa laga heli karaa: https://www.mayoclinic.org/diseases-conditions/undescended-testicle/diagnosis-treatment/drc-20352000
10. Mayo Clinic: Mayo Laboratories [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1995–2018. Aqoonsiga Tijaabada: AMH: Antimullerian Hormone (AMH), Serum: Clinical and Interpretive; [daliishaday 2018 Dec 11]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/89711
11. Mayo Clinic: Mayo Laboratories [Internet]. Aasaaska Mayo ee Caafimaadka Caafimaadka iyo Cilmi-baarista; c1995–2018. Aqoonsiga Tijaabada: AMH: Antimullerian Hormone (AMH), Serum: Guudmarka; [daliishaday 2018 Dec 11]; [ilaa 2 shaashad]. Waxaa laga heli karaa: https://www.mayocliniclabs.com/test-catalog/Overview/89711
12. Machadka Wadnaha, Sambabka, iyo Machadka Dhiiga [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Tijaabooyinka Dhiigga; [daliishaday 2018 Dec 11]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://www.nhlbi.nih.gov/health-topics/blood-tests
13. NIH Maktabadda Qaranka ee Caafimaadka: Tixraaca Hoyga Guryaha [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Hidda-wadaha AMH; 2018 Dec 11 [daliishaday 2018 Dec 11]; [ilaa 3 shaashad]. Waxaa laga heli karaa: https://ghr.nlm.nih.gov/gene/AMH
14. NIH Maktabadda Qaranka ee Caafimaadka: Tixraaca Hoyga Guryaha [Internet]. Bethesda (MD): Waaxda Caafimaadka iyo Adeegyada Aadanaha ee Mareykanka; Aplasia Müllerian iyo hyperandrogenism; 2018 Dec 11 [daliishaday 2018 Dec 11]; [ilaa 2 shaashad].Waxaa laga heli karaa: https://ghr.nlm.nih.gov/condition/mullerian-aplasia-and-hyperandrogenism
15. Associates Medicine taranka ee New Jersey [Internet]. RMANJ; c2018. Hormone Anti-Mullerian (AMH) Tijaabinta keydka ugxanta; 2018 Sep 14 [daliishaday 2018 Dec 11]; [ilaa 4 shaashadood]. Waxa laga heli karaa: https://www.rmanj.com/anti-mullerian-hormone-amh-testing-of-ovarian-reserve
16. Sagsak E, Onder A, Ocal FD, Tasci Y, Agladioglu SY, Cetinkaya S Aycan Z. Primary Amenorrhea Secondary to Mullerian Anomaly. J Case Rep [Internet]. 2014 Mar 31 [daliishaday 2018 Dec 11]; Arrin Gaar ah: doi: 10.4172 / 2165-7920.S1-007. Waxaa laga heli karaa: https://www.omicsonline.org/open-access/primary-amenorrhea-secondary-to-mullerian-anomaly-2165-7920.S1-007.php?aid=25121

Macluumaadka ku yaal boggan waa in aan loo isticmaalin beddel daryeel caafimaad oo xirfad leh ama talo. La xiriir bixiye daryeel caafimaad haddii aad su'aalo ka qabtid caafimaadkaaga.