Glucagonoma

Glucagonoma waa buro aad dhif u ah unugyada istaraatiijka ee xammeetida, taas oo horseedda xad-dhaaf hormoonka glucagon ee dhiigga ku jira.

Glucagonoma badanaa waa kansar (malignant). Kansarku wuxuu u egyahay inuu fido oo ka sii daro.

Kansarkaani wuxuu saameeyaa unugyada yar-yar ee xammeetida. Sidaa darteed, unugyada jasiiraddu waxay soo saaraan wax badan oo ka mid ah hormoonka glucagon.

Sababta lama oga. Sababaha hidaha ayaa door ka ciyaara xaaladaha qaarkood. Taariikhda qoyska ee cilladda noocyada badan ee loo yaqaan 'endocrine neoplasia type I (MEN I)' ayaa ah arrin khatar ku ah.

Calaamadaha glucagonoma waxaa ka mid noqon kara mid ka mid ah kuwan soo socda:

• Dulqaad la'aanta Gulukooska (jirku wuxuu dhibaato ku qabaa kalagoynta sonkorta)
• Sonkorta dhiiga oo sareysa (hyperglycemia)
• Shuban
• Haraad xad dhaaf ah (sonkorta dhiiga oo saraysa darteed)
• Kaadida oo soo noqnoqota (sonkorta dhiiga oo saraysa darteed)
• Rabitaanka cuntada oo kordhay
• Af iyo carab bararsan
• Kaadida Habeenkii (habeenkii)
• Finan maqaarka ah oo ka soo baxa wejiga, caloosha, badhida, ama cagaha soo baxa ama taga, oo wareega
• Miisaanka oo yaraada

Xaaladaha badankood, kansarku wuxuu horey ugu faafay beerka markii la ogaado.

Bixiyaha xanaanada caafimaadka ayaa sameyn doona baaritaan jireed wuxuuna weydiin doonaa taariikhdaada caafimaad iyo astaamahaaga.

Tijaabooyinka la qaadi karo waxaa ka mid ah:

• CT iskaanka caloosha
• Heerka Glucagon ee dhiiga ku jira
• Heerka sonkorta dhiigga

Qalliin si looga saaro buro badanaa waa lagula taliyaa. Burooyinka inta badan kama jawaabaan daweynta kiimoteraabiga.

Waad yareyn kartaa diiqada jirrada adoo ku biiraya kooxda taageerta kansarka. La wadaagida dadka kale ee leh khibradaha guud iyo dhibaatooyinka ayaa kaa caawin kara inaadan kali dareemin.

Qiyaastii 60% burooyinkaan waa kansar. Waa wax caadi ah in kansarkan uu ku faafo beerka. Qiyaastii 20% dadka ayaa lagu bogsiin karaa qalliin.

Haddii buro ay ku taal xammeetida oo keliya qalliinka si looga soo saaro waa lagu guuleystaa, dadku waxay leeyihiin heerka badbaadada 5-sano ee ah 85%.

Kansarku wuxuu ku faafi karaa beerka. Heerka sonkorta dhiigga ee sareeya wuxuu sababi karaa dhibaatooyin xagga dheef-shiid kiimikaadka iyo dhaawaca unugyada.

Wac adeeg bixiyahaaga haddii aad dareento astaamaha glucagonoma.

Ragga I - glucagonoma

• Qanjirada 'Endocrine'

Websaydhka Machadka Kansarka Qaranka. Daaweynta qanjirada 'Pancreatic neuroendocrine burooyinka' (burooyinka unugyada yar yar)) (PDQ) - nooc xirfad-yaqaan caafimaad ah. www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq. La cusbooneysiiyay Febraayo 8, 2018. La helay Noofambar 12, 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Kansarka nidaamka endocrine. Gudaha: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology. 5aad. Philadelphia, PA: Elsevier Saunders; 2014: cutubka 71.

Vella A. Hormoonnada caloosha iyo mindhicirka iyo burooyinka endocrine gut. Gudaha: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Buugga Buugga Endocrinology. 13aad. Philadelphia, PA: Elsevier; 2016: cutubka 38.