Heerarka kolestaroolka dhiigga oo sarreeya

Kalastarol waa dufan (sidoo kale loo yaqaan lipid) jirkaagu u baahan yahay inuu si sax ah ugu shaqeeyo. Kalastarool aad u xun ayaa kordhin kara fursaddaada qaadista cudurka wadnaha, istaroogga, iyo dhibaatooyinka kale.

Ereyga caafimaad ee kolestaroolka dhiigga sareeya waa cilladaha baruurta, 'hyperlipidemia', ama 'hypercholesterolemia'.

Waxaa jira noocyo badan oo kolestarool ah. Kuwa ugu badan ee laga hadlay waa:

• Wadarta kolestaroolka - dhammaan kolestaroollada la isku daro
• Cufnaanta sare ee lipoprotein (HDL) kolestaroolka - badanaa loo yaqaan kolestaroolka "wanaagsan"
• Cufnaanta hoose ee lipoprotein (LDL) kolestaroolka - badanaa loo yaqaan kolestaroolka "xun"

Dad badan, heerarka kolestaroolka aan caadiga ahayn waxaa qayb ahaan sabab u ah qaab nololeed aan caafimaad qabin. Tani badanaa waxay kujirtaa cunista cunto dufan badan leh. Waxyaabaha kale ee nolosha lagu cabiro waa:

• Miisaan culus
• Jimicsi la’aan

Xaaladaha caafimaad qaarkood waxay kaloo u horseedi karaan kolestarool aan caadi ahayn, oo ay ka mid yihiin:

• Sonkorowga
• Cudurka kilyaha
• Cudurka 'Polycystic ovary syndrome'
• Uurka iyo xaaladaha kale ee kordhiya heerarka hoormoonka haweenka
• Qanjirka 'thyroid' qanjirka 'thyroid'

Daawooyinka sida kaniiniyada xakameynta dhalmada qaarkood, durayo (kaniiniyada biyaha), beta-blockers, iyo daawooyinka qaar ee loo isticmaalo daaweynta niyad jabka ayaa sidoo kale sare u qaadi kara heerarka kalastarolka. Dhibaatooyin dhowr ah oo loo gudbiyo qoysaska ayaa horseeda heerarka kalastaroolka aan caadiga ahayn iyo heerarka triglyceride. Waxaa ka mid ah:

• Isku-darka 'hyperlipidemia' ee qoyska
• Qoyska dysbetalipoproteinemia
• Qoyska 'hypercholesterolemia'
• Hypertriglyceridemia qoyska

Sigaar cabiddu ma keento heerarka kolestaroolka ee sarreeya, laakiin waxay yareyn kartaa kolestaroolkaaga HDL (wanaagsan).

Tijaabada kolestaroolka waxaa loo sameeyaa si loo ogaado cilladda dufanka leh. Khubaro kala duwan ayaa kugula talinaysa da 'kala duwan oo ay bilaabaan dadka waaweyn.

• Da'da lagu bilaabayo ee lagu talinayo waa inta udhaxeysa 20 ilaa 35 ragga iyo 20 ilaa 45 dumarka.
• Dadka waaweyn ee leh heerar kalastarool caadi ah uma baahna in baaritaanka lagu celiyo 5 sano.
• Ku celi tijaabinta sida ugu dhakhsaha badan haddii isbeddello ku yimaadaan qaab nololeedka (oo ay ku jiraan miisaanka oo kordha iyo cuntada).
• Dadka waaweyn ee leh taariikh kolestarool sare, sonkorow, dhibaatooyin kelyaha, wadne xanuun, iyo xaalado kale ayaa u baahan baaritaan dheeri ah.

Waa muhiim inaad la shaqeyso bixiyaha xanaanada caafimaadkaaga si aad u dejiso hadafyadaada kolestaroolka. Tilmaamaha cusub ayaa dhakhaatiirta ka fogeynaya bartilmaameedka heerarka gaarka ah ee kolestaroolka. Taabadalkeed, waxay kugula talinayaan dawooyin iyo qiyaaso kaladuwan iyadoo kuxiran taariikhda qofka iyo muuqaalka halista halista. Tilmaamahan ayaa isbeddelaya waqti ka waqti kolba haddii macluumaad dheeraad ah oo ku saabsan daraasadaha cilmi baarista la helayo.

Bartilmaameedyada guud waa:

• LDL: 70 illaa 130 mg / dL (tirooyinka hoose ayaa kafiican)
• HDL: In kabadan 50 mg / dL (tirooyin ka sareeya ayaa kafiican)
• Wadarta kolestaroolka: In ka yar 200 mg / dL (tirooyinka hoose ayaa ka fiican)
• Triglycerides: 10 illaa 150 mg / dL (tirooyinka hoose ayaa ka fiican)

Haddii natiijooyinka kolestaroolkaagu ay yihiin kuwo aan caadi ahayn, waxaa laga yaabaa inaad sidoo kale yeelato baaritaanno kale sida:

• Tijaabada sonkorta dhiigga (gulukooska) si loo baaro sonkorowga
• Imtixaanada shaqada kilyaha
• Tijaabooyinka shaqada qanjirka 'thyroid' si loo raadiyo qanjirka 'thyroid' oo aan firfircooneyn

Talaabooyinka aad qaadi karto si aad u hagaajisid heerarka kolestaroolkaaga iyo si looga hortago cudurka wadnaha iyo wadne qabadka waxaa ka mid ah:

• Sigaar joojinta Tani waa isbeddelka kaliya ee ugu weyn ee aad sameyn karto si aad u yareyso halista wadno-qabad iyo istaroog.
• Cun cuntooyin dabiici ahaan dufanku ku yar yahay. Kuwaas waxaa ka mid ah miraha isku dhan, miraha, iyo khudaarta.
• Isticmaal dufanno dufanku ku yar yahay, suugo, iyo dhaymo.
• Ka fogow cuntooyinka ay ku badan yihiin dufanka buuxa.
• Samee jimicsi joogto ah.
• Miisaankaaga dhin haddii aad miisaan culus tahay.

Bixiyahaagu waxaa laga yaabaa inuu rabo inaad daawo u qaadato kolestaroolka haddii isbeddelada hab-nololeedka aysan shaqeynayn. Tani waxay ku xirnaan doontaa:

• Dadaada
• Haddii aad qabto iyo haddii kaleba inaad qabtid cudurka wadnaha, sonkorowga, ama dhibaatooyin kale oo qulqulka dhiigga ah
• Haddii aad sigaar cabtid ama aad cayilan tahay
• Haddii aad qabtid dhiig kar ama sonkorow

Waxay u badan tahay inaad u baahato dawo si aad hoos ugu dhigto kolestaroolkaaga:

• Haddii aad qabtid cudur wadne ama sonkorow
• Haddii aad qatar ugu jirto cudurka wadnaha (xitaa haddii aadan weli wax dhibaato ah wadnaha qabin)
• Haddii kolestaroolkaaga LDL uu yahay 190 mg / dL ama ka sareeya

Ku dhowaad qof kasta oo kale wuxuu ka heli karaa faa'iidooyinka caafimaadka kolestaroolka LDL ee ka hooseeya 160 illaa 190 mg / dL.

Waxaa jira dhowr nooc oo daawooyin ah oo ka caawiya hoos u dhigidda heerarka kolestaroolka dhiigga. Daawooyinku waxay u shaqeeyaan siyaabo kala duwan. Statins waa nooc ka mid ah daroogada hoos u dhigta kolestaroolka waxaana la xaqiijiyay inay yareyneyso fursada wadne xanuunka. Daawooyin kale ayaa la heli karaa haddii halistaadu sareyso oo statins aysan hoos u dhigin heerarka kolestaroolkaaga. Kuwaas waxaa ka mid ah ezetimibe iyo PCSK9 xakameeyayaasha.

Heerarka sare ee kolestaroolka waxay u horseedi karaan adkaanshaha halbowlayaasha, oo sidoo kale loo yaqaan 'atherosclerosis'. Tani waxay dhacdaa marka dufanka, kolestaroolka, iyo walxaha kale ay ka soo baxaan derbiyada halbowlayaasha oo ay samaystaan ​​dhismooyin adag oo loo yaqaan 'plaques'.

Waqti ka dib, dabarradani waxay xannibayaan xididdada dhiigga waxayna sababaan cudurrada wadnaha, istaroogga, iyo calaamadaha kale ama dhibaatooyinka jirka oo dhan.

Dhibaatooyinka loo soo gudbiyo qoysaska badanaa waxay keenaan heerar sare oo kolestarool ah oo ay adag tahay in la xakameeyo.

Kalastarol - sare; Ciladaha baruurta; Hyperlipoproteinemia; Hyperlipidemia; Dyslipidemia; Hypercholesterolemia

• Angina - dheecaan
• Angioplasty iyo stent - dheecaan wadnaha ah
• Dawooyinka Antiplatelet - Daawadayaasha P2Y12
• Aspirin iyo wadne xanuun
• Firfircoonow wadnahaaga kadib
• Firfircoonow markaad xanuun wadne qabtid
• Butter, margarine, iyo saliidaha wax lagu kariyo
• Kateetarka wadnaha - dheecaan
• Kalastarol iyo qaab nololeedka
• Kalastaroolka - daaweynta daroogada
• Kalastaroolka - waxa aad weydiiso dhakhtarkaaga
• Xakamaynta dhiig karkaaga
• Sonkorowga - ka-hortagga wadno-qabadka iyo istaroogga
• Dufanka cuntada ayaa la sharaxay
• Tilmaamaha cuntada degdega ah
• Wadne qabad - dheecaan
• Qalliinka wadnaha - dheecaan
• Qalliinka wadnaha lagu maro - yaraanta soo-baxa - dheecaanka
• Waxyaabaha halista u ah cudurka wadnaha
• Wadne istaag - dheecaanno iyo durayo
• Wadne jabka - kormeerka guriga
• Wadnaha wadnaha - dheecaan
• Sida loo aqriyo sumadaha cuntada
• Cunto-milix-yar
• Cuntada badda Mediterranean
• Faalig - dheecaan
• Nooca sonkorowga 2aad - waxaad weydiiso dhakhtarkaaga

• Soosaarayaasha kolestaroolka
• Cudurka halbowlayaasha wadnaha
• Kalastarool
• Nidaamka koritaanka ee atherosclerosis

Genest J, Libby P. Dhibaatooyinka Lipoprotein iyo cudurada wadnaha. Gudaha: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Cudurka Wadnaha ee Braunwald: Buug-tilmaameedka Daaweynta Wadnaha iyo Xididdada. 11aad. Philadelphia, PA: Elsevier; 2019: cutubka 48.

Grundy SM, Stone NJ, Bailey AL, iyo al. Tilmaamaha ku saabsan maareynta kolestaroolka dhiigga: warbixin ku saabsan Kulliyadda Caafimaadka Wadnaha ee Mareykanka / Ururka Wadnaha ee Mareykanka ee Tilmaamaha Tababarka Caafimaadka . J Am Coll Cardiol. 2019; 73 (24); e285-e350. PMID: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

Robinson JG. Cilladaha dheef-shiid kiimikaadka. Gudaha: Goldman L, Schafer AI, eds. Daawada Goldman-Cecil. 26aad. Philadelphia, PA: Elsevier; 2020: cutubka 195.

Bayaanka talobixinta ugu dambeysa ee Kooxda Ka-hortagga Adeegyada Mareykanka. Isticmaalka Statin ee kahortaga aasaasiga ah ee cudurka wadnaha iyo xididdada ee dadka qaangaarka ah: daaweynta kahortagga. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication. La cusbooneysiiyay Nofeembar 13, 2016. Waxaa la helay Febraayo 24, 2020.

Xoogagga Adeegyada Ka-hortagga ee Mareykanka; Bibbins-Domingo K, Grossman DC, Curry SJ, iyo al. Baadhitaanka cilladaha baruurta ee carruurta iyo qaan-gaarka: Bayaanka talo-bixinta ee Kooxda Ka-hortagga Adeegyada Ka-hortagga Mareykanka. JAMA. 2016; 316 (6): 625-633. PMID: 27532917 pubmed.ncbi.nlm.nih.gov/27532917/.